Home Research COVID-19 Services Publications People Teaching Job Opening News Forum Lab Only
Online Services

I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

Yang Zhang's Research Group

    Department of Computational Medicine and Bioinformatics
    Department of Biological Chemistry
    University of Michigan Medical School
    100 Washtenaw Avenue
    Ann Arbor, MI 48109-2218
    Phone: (734)647-1549
    Fax: (734)615-6553
    Email: yangzhanglabumich.edu
We are interested in:
I-TASSER model vs crystal structure of T0604_1, a CASP9 FM target
Determining structure and function of protein molecules is a cornerstone of modern biology and medicine. One of the main focuses of our lab is to develop computational methods to predict 3-dimensional structure of protein molecules from amino acid sequence, and to deduce the biological functions based on the sequence-to-structure-to-function paradigm. The second focus of our lab is to combine computational algorithms and biochemistry experiments to design new protein molecules with enhanced functionality beyond nature proteins. We are also working on modeling ligand-protein and protein-protein interactions, with particular interest in new drug screening targeting G protein-coupled receptors in the human genome ( >> read more ... ).

Zhang Lab news:

yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218