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I-TASSER QUARK LOMETS COACH COFACTOR MUSTER SEGMER FG-MD ModRefiner REMO SPRING COTH BSpred SVMSEQ ANGLOR BSP-SLIM SAXSTER ThreaDom EvoDesign GPCR-I-TASSER BindProf BindProfX ResQ IonCom STRUM

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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP TM-fold DECOYS POTENTIAL RW HPSF CASP7 CASP8 CASP9 CASP10 CASP11 CASP12


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The training and test benchmark datasets used in the COACH paper can be downloaded below:

Training set (400 proteins, 908 bound ligands) Experimental structure Ligand structure Binding residues
Test set (500 proteins, 814 bound ligands) Experimental structure, I-TASSER model Ligand structure Binding residues


References:
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment, Bioinformatics, 29:2588-2595 (2013). (download the PDF file)
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions. Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

 


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