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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Kappa-type opioid receptor
Species	Cavia porcellus (Guinea pig)
Gene	OPRK1
Synonym	K-OR-1 KOR-1
Disease	N/A for non-human GPCRs
Length	380
Amino acid sequence	MGRRRQGPAQPASELPARNACLLPNGSAWLPGWAEPDGNGSAGPQDEQLEPAHISPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIILGGTKVREDVDIIECSLQFPDDDYSWWDLFMKICVFVFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFIICWTPIHIFILVEALGSTSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPIKMRMERQSTSRVRNTVQDPAYMRNVDGVNKPV
UniProt	P41144
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3952
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL607277
Molecular formula	C13H24N2O
IUPAC name	N-methyl-N-[(1S,2R)-2-pyrrolidin-1-ylcyclohexyl]acetamide
Molecular weight	224.348
Hydrogen bond acceptor	2
Hydrogen bond donor	0
XlogP	1.6
Synonyms	N-Methyl-N-[(1S)-2alpha-(1-pyrrolidinyl)cyclohexan-1alpha-yl]acetamide
Inchi Key	AQVPSKYQMCFDGE-QWHCGFSZSA-N
Inchi ID	InChI=1S/C13H24N2O/c1-11(16)14(2)12-7-3-4-8-13(12)15-9-5-6-10-15/h12-13H,3-10H2,1-2H3/t12-,13+/m0/s1
PubChem CID	14771413
ChEMBL	CHEMBL607277
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Control	96.45 %	PMID2172538	ChEMBL
Control	111.88 %	PMID2172538	ChEMBL

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