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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
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GPCR

Name	C-C chemokine receptor type 10
Species	Homo sapiens (Human)
Gene	CCR10
Synonym	CCR-10 CCR10 CC-CKR-10 G-protein coupled receptor 2 GPR-2 C-C CKR-10 [ Show all ]
Disease	Inflammatory disease
Length	362
Amino acid sequence	MGTEATEQVSWGHYSGDEEDAYSAEPLPELCYKADVQAFSRAFQPSVSLTVAALGLAGNGLVLATHLAARRAARSPTSAHLLQLALADLLLALTLPFAAAGALQGWSLGSATCRTISGLYSASFHAGFLFLACISADRYVAIARALPAGPRPSTPGRAHLVSVIVWLLSLLLALPALLFSQDGQREGQRRCRLIFPEGLTQTVKGASAVAQVALGFALPLGVMVACYALLGRTLLAARGPERRRALRVVVALVAAFVVLQLPYSLALLLDTADLLAARERSCPASKRKDVALLVTSGLALARCGLNPVLYAFLGLRFRQDLRRLLRGGSCPSGPQPRRGCPRRPRLSSCSAPTETHSLSWDN
UniProt	P46092
Protein Data Bank	N/A
GPCR-HGmod model	P46092
3D structure model	This predicted structure model is from GPCR-EXP P46092.
BioLiP	N/A
Therapeutic Target Database	T71054
ChEMBL	CHEMBL2321628
IUPHAR	67
DrugBank	N/A

Ligand

Name	CHEMBL3733316
Molecular formula	C26H25ClN6O5S
IUPAC name	methyl N-[7-(2-chloroanilino)-6-(4-phenylpiperidine-1-carbonyl)pyrazolo[1,5-a]pyrimidin-3-yl]sulfonylcarbamate
Molecular weight	569.033
Hydrogen bond acceptor	8
Hydrogen bond donor	2
XlogP	4.2
Synonyms	SCHEMBL14471765 Methyl 7-(2-chlorophenylamino)-6-(4-phenylpiperidine-1-carbonyl)pyrazolo[1,5-a]pyrimidin-3-ylsulfonylcarbamate PHCWIKWCBUDOKR-UHFFFAOYSA-N
Inchi Key	PHCWIKWCBUDOKR-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H25ClN6O5S/c1-38-26(35)31-39(36,37)22-16-29-33-23(30-21-10-6-5-9-20(21)27)19(15-28-24(22)33)25(34)32-13-11-18(12-14-32)17-7-3-2-4-8-17/h2-10,15-16,18,30H,11-14H2,1H3,(H,31,35)
PubChem CID	71178953
ChEMBL	CHEMBL3733316
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Experimental Data

Parameter	Value	Reference	Database source
Inhibition	99.6 %	None	ChEMBL

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