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| Name | Mu-type opioid receptor |
|---|---|
| Species | Mus musculus (Mouse) |
| Gene | Oprm1 |
| Synonym | opioid receptor, mu 1 opioid receptor OP3 Mu receptor MOR-1 [ Show all ] |
| Disease | N/A for non-human GPCRs |
| Length | 398 |
| Amino acid sequence | MDSSAGPGNISDCSDPLAPASCSPAPGSWLNLSHVDGNQSDPCGPNRTGLGGSHSLCPQTGSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGNILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQQNSARIRQNTREHPSTANTVDRTNHQLENLEAETAPLP |
| UniProt | P42866 |
| Protein Data Bank | 4dkl, 5c1m, 6dde, 6ddf |
| GPCR-HGmod model | N/A |
| 3D structure model | This structure is from PDB ID 4dkl. |
| BioLiP | BL0416752, BL0416751, BL0321492, BL0224753, BL0224754, BL0224755,BL0224756, BL0321491 |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL2858 |
| IUPHAR | 319 |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 1510 |  CHEMBL113995 | C25H31N5O7 | 513.551 | 8 / 7 | -2.8 | No |
| 2413 |  CHEMBL595015 | C22H28N4O | 364.493 | 4 / 0 | 4.8 | Yes |
| 3356 |  CHEMBL317269 | C23H31NO4 | 385.504 | 5 / 1 | 2.5 | Yes |
| 3530 |  CHEMBL38576 | C21H24Cl2N2O | 391.336 | 2 / 0 | 4.6 | Yes |
| 4397 |  CHEMBL365803 | C35H40N6O5 | 624.742 | 6 / 7 | 2.6 | No |
| 4398 |  CHEMBL364010 | C35H40N6O5 | 624.742 | 6 / 7 | 2.6 | No |
| 4425 |  CHEMBL2147922 | C25H24ClF3N2O2 | 476.924 | 7 / 3 | N/A | N/A |
| 4642 |  CHEMBL593613 | C21H26N4O | 350.466 | 4 / 1 | 4.5 | Yes |
| 4702 |  CHEMBL2334770 | C35H38N6O5 | 622.726 | 6 / 6 | 2.3 | No |
| 4704 |  CHEMBL2334768 | C35H38N6O5 | 622.726 | 6 / 6 | 2.3 | No |
| 4910 |  (2E,4E)-N-isobutyltetradeca-2,4-dienamide | C18H33NO | 279.468 | 1 / 1 | 6.6 | No |
| 5961 |  CHEMBL151416 | C29H36N2O | 428.62 | 3 / 1 | 6.5 | No |
| 6005 |  CHEMBL1834895 | C44H51N3O9 | 765.904 | 12 / 4 | 3.2 | No |
| 6007 |  CHEMBL1834901 | C44H51N3O9 | 765.904 | 12 / 4 | 3.2 | No |
| 6767 |  CHEMBL1270475 | C27H28N2O2 | 412.533 | 4 / 2 | 4.1 | Yes |
| 553278 |  82824-01-9 | C38H42N4O6 | 650.776 | 10 / 4 | 4.0 | No |
| 7385 |  CHEMBL3215911 | C35H39Cl2N3O4 | 636.614 | 6 / 5 | N/A | No |
| 8219 |  Ketobemidone | C15H21NO2 | 247.338 | 3 / 1 | 1.0 | Yes |
| 9528 |  CHEMBL121946 | C38H54N8O10 | 782.896 | 11 / 10 | -1.5 | No |
| 9605 |  CHEMBL2163544 | C26H29N3O4 | 447.535 | 6 / 4 | 0.5 | Yes |
| 9664 |  CHEMBL149795 | C29H36N2O2 | 444.619 | 4 / 2 | 5.5 | No |
| 10413 |  CHEMBL285378 | C26H29N3O6 | 479.533 | 7 / 3 | -1.1 | Yes |
| 11346 |  CHEMBL93614 | C22H29NO2 | 339.479 | 3 / 2 | 4.5 | Yes |
| 12322 |  CHEMBL316172 | C18H21NO3S | 331.43 | 4 / 3 | 2.9 | Yes |
| 12562 |  Piperidine, 1-[(2E,4E)-1-oxo-2,4-tetradecadienyl]- | C19H33NO | 291.479 | 1 / 0 | 6.3 | No |
| 13262 |  CHEMBL1834903 | C42H49N3O8 | 723.867 | 11 / 5 | 2.3 | No |
| 13266 |  CHEMBL1834902 | C42H49N3O8 | 723.867 | 11 / 5 | 2.3 | No |
| 13568 |  CHEMBL1834898 | C46H55N3O9 | 793.958 | 12 / 4 | 4.3 | No |
| 13605 |  CHEMBL3264748 | C31H34N2O5 | 514.622 | 6 / 1 | 3.9 | No |
| 14801 |  CHEMBL3217021 | C29H35Cl2N3O4 | 560.516 | 6 / 6 | N/A | No |
| 15358 |  CHEMBL2147917 | C25H26N2O3 | 402.494 | 5 / 2 | 3.4 | Yes |
| 15707 |  CHEMBL2419124 | C30H30ClN3O4 | 532.037 | 6 / 3 | 2.8 | No |
| 18311 |  CHEMBL2387739 | C31H36ClN3O5 | 566.095 | 6 / 4 | N/A | No |
| 19000 |  CHEMBL520557 | C29H30N2O3 | 454.57 | 4 / 2 | 3.6 | Yes |
| 19012 |  BDBM85541 | C28H35NO4 | 449.591 | 5 / 2 | 3.6 | Yes |
| 19015 |  BDBM85540 | C28H35NO4 | 449.591 | 5 / 2 | 3.6 | Yes |
| 19789 |  UNII-5F4WO3BVS9 | C16H29NO | 251.414 | 1 / 1 | 5.5 | No |
| 19799 |  CHEMBL98626 | C22H28ClNO | 357.922 | 2 / 1 | 6.1 | No |
| 442449 |  CHEMBL3339376 | C21H24N2O3 | 352.434 | 5 / 2 | 1.2 | Yes |
| 20044 |  CHEMBL2016674 | C21H24N2O3 | 352.434 | 5 / 2 | 1.2 | Yes |
| 20609 |  CHEMBL185668 | C31H35N3O3 | 497.639 | 4 / 1 | 4.7 | Yes |
| 20854 |  CHEMBL2315356 | C25H30ClF3N2O5 | 530.969 | 9 / 4 | N/A | No |
| 21204 |  CHEMBL2437062 | C27H27N3O5 | 473.529 | 6 / 1 | 3.1 | Yes |
| 23256 |  CHEMBL2114080 | C17H25NO2 | 275.392 | 3 / 0 | 3.7 | Yes |
| 24367 |  CHEMBL298314 | C26H27NO5 | 433.504 | 6 / 2 | 2.6 | Yes |
| 24512 |  171807-62-8 | C32H39N5O5 | 573.694 | 6 / 6 | 2.1 | No |
| 442636 |  CHEMBL3326359 | C22H25NO5 | 383.444 | 6 / 0 | 3.0 | Yes |
| 24764 |  CHEMBL611413 | C24H33NO4 | 399.531 | 5 / 0 | 2.9 | Yes |
| 25232 |  CHEMBL97509 | C21H33NO | 315.501 | 2 / 1 | 6.2 | No |
| 25373 |  CHEMBL2418741 | C18H23NO4 | 317.385 | 5 / 2 | 1.2 | Yes |
| 25653 |  CHEMBL185906 | C23H25N3O2 | 375.472 | 4 / 1 | 2.9 | Yes |
| 27015 |  CHEMBL271026 | C16H21NO3 | 275.348 | 4 / 2 | -0.9 | Yes |
| 27905 |  DIPPA | C22H23Cl2N3OS | 448.406 | 4 / 0 | 6.0 | No |
| 28034 |  CHEMBL434542 | C30H36N2O2 | 456.63 | 3 / 1 | 6.1 | No |
| 28548 |  CHEMBL2147918 | C25H27ClN2O3 | 438.952 | 5 / 3 | N/A | N/A |
| 28680 |  CHEMBL318213 | C32H30N2O3 | 490.603 | 4 / 3 | 4.9 | Yes |
| 28716 |  CHEMBL1270474 | C27H30N2O2 | 414.549 | 4 / 2 | 4.7 | Yes |
| 29201 |  CHEMBL3264746 | C34H34N2O5 | 550.655 | 6 / 1 | 4.6 | No |
| 30356 |  morphine | C17H19NO3 | 285.343 | 4 / 2 | 0.8 | Yes |
| 30363 |  Morphinan-3,6.alpha.-diol, 7,8-didehydro-4,5.alpha.-epoxy-17-methyl- | C17H19NO3 | 285.343 | 4 / 2 | 0.8 | Yes |
| 31099 |  CHEMBL26883 | C25H30N2O5 | 438.524 | 6 / 3 | -0.4 | Yes |
| 31363 |  oxycodone | C18H21NO4 | 315.369 | 5 / 1 | 1.2 | Yes |
| 32225 |  CHEMBL303301 | C27H34N2O3 | 434.58 | 4 / 3 | 4.6 | Yes |
| 35547 |  CHEMBL424987 | C29H30N6O2 | 494.599 | 6 / 2 | 4.4 | Yes |
| 35593 |  SCHEMBL1988127 | C30H37N3O2 | 471.645 | 4 / 1 | 5.1 | No |
| 39275 |  CHEMBL2442635 | C16H21NOS | 275.41 | 2 / 1 | 4.3 | Yes |
| 40534 |  CHEMBL605307 | C22H28N4O | 364.493 | 4 / 0 | 4.8 | Yes |
| 40820 |  CHEMBL15032 | C42H49N5O7 | 735.882 | 8 / 6 | 3.3 | No |
| 43121 |  Deltorphin I | C37H52N8O10 | 768.869 | 11 / 10 | -1.7 | No |
| 43659 |  CHEMBL148020 | C18H25NO | 271.404 | 2 / 1 | 2.9 | Yes |
| 43662 |  CHEMBL357859 | C18H25NO | 271.404 | 2 / 1 | 2.9 | Yes |
| 45803 |  CHEMBL610549 | C35H47N5O12S | 761.844 | 15 / 8 | -7.1 | No |
| 45804 |  beta-NFA conjugate 3 | C35H47N5O12S | 761.844 | 15 / 8 | -7.1 | No |
| 443486 |  CHEMBL3326360 | C21H23NO5 | 369.417 | 6 / 1 | 2.7 | Yes |
| 47620 |  CHEMBL3264745 | C29H30N2O5 | 486.568 | 6 / 1 | 3.3 | Yes |
| 48128 |  CHEMBL2147920 | C25H23F3N2O2 | 440.466 | 7 / 2 | 4.3 | Yes |
| 49021 |  CHEMBL458089 | C30H40N2O4 | 492.66 | 5 / 2 | 2.8 | Yes |
| 49135 |  CHEMBL365886 | C28H31N3O2 | 441.575 | 4 / 2 | 4.5 | Yes |
| 50080 |  CHEMBL2437067 | C26H25N3O5 | 459.502 | 6 / 2 | 2.7 | Yes |
| 51115 |  CHEMBL3215908 | C30H37Cl2N3O4 | 574.543 | 6 / 6 | N/A | No |
| 51116 |  CHEMBL3216801 | C30H37Cl2N3O4 | 574.543 | 6 / 6 | N/A | No |
| 52705 |  CHEMBL1770605 | C22H21NO3 | 347.414 | 4 / 0 | 4.6 | Yes |
| 52988 |  CHEMBL2163546 | C26H28N2O5 | 448.519 | 6 / 4 | 0.8 | Yes |
| 53182 |  CHEMBL611146 | C22H29NO4 | 371.477 | 5 / 0 | 2.4 | Yes |
| 53475 |  CHEMBL297933 | C29H31NO5 | 473.569 | 6 / 2 | 3.7 | Yes |
| 56058 |  CHEMBL476540 | C28H28N2O3 | 440.543 | 4 / 2 | 3.2 | Yes |
| 57788 |  CHEMBL2164300 | C26H36N2O4 | 440.584 | 5 / 3 | 2.0 | Yes |
| 58916 |  CHEMBL365863 | C29H33N3O2 | 455.602 | 4 / 2 | 4.1 | Yes |
| 59196 |  CHEMBL330138 | C19H25NOS | 315.475 | 3 / 1 | 4.8 | Yes |
| 559116 |  CHEMBL2147914 | C24H25ClN2O3 | 424.925 | 5 / 4 | N/A | N/A |
| 59380 |  CHEMBL2315359 | C27H37ClN2O5 | 505.052 | 6 / 4 | N/A | No |
| 59965 |  CHEMBL2442643 | C19H31NO | 289.463 | 1 / 0 | 5.3 | No |
| 60042 |  CHEMBL148086 | C17H22N2O | 270.376 | 3 / 1 | 1.5 | Yes |
| 60045 |  CHEMBL149491 | C17H22N2O | 270.376 | 3 / 1 | 1.5 | Yes |
| 60294 |  CHEMBL611415 | C24H33NO3 | 383.532 | 4 / 0 | 3.3 | Yes |
| 61776 |  SCHEMBL1651439 | C28H33ClN2O5 | 513.031 | 7 / 3 | N/A | No |
| 62142 |  CHEMBL92303 | C22H35NO2 | 345.527 | 3 / 1 | 4.4 | Yes |
| 62333 |  BU-46 | C26H31NO4 | 421.537 | 5 / 2 | 2.8 | Yes |
| 62335 |  BU-47 | C26H31NO4 | 421.537 | 5 / 2 | 2.8 | Yes |
| 63109 |  CHEMBL108076 | C24H33N3O2 | 395.547 | 3 / 2 | 3.8 | Yes |
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