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| Name | Neuropeptide FF receptor 2 |
|---|---|
| Species | Homo sapiens (Human) |
| Gene | NPFFR2 |
| Synonym | NPFF2 receptor Neuropeptide G-protein coupled receptor GPR74 G-protein coupled receptor HLWAR77 G-protein coupled receptor 74 [ Show all ] |
| Disease | N/A |
| Length | 522 |
| Amino acid sequence | MNSFFGTPAASWCLLESDVSSAPDKEAGRERRALSVQQRGGPAWSGSLEWSRQSAGDRRRLGLSRQTAKSSWSRSRDRTCCCRRAWWILVPAADRARRERFIMNEKWDTNSSENWHPIWNVNDTKHHLYSDINITYVNYYLHQPQVAAIFIISYFLIFFLCMMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPITLLDNIIAGWPFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPKLTIKTAFVIIMIIWVLAITIMSPSAVMLHVQEEKYYRVRLNSQNKTSPVYWCREDWPNQEMRKIYTTVLFANIYLAPLSLIVIMYGRIGISLFRAAVPHTGRKNQEQWHVVSRKKQKIIKMLLIVALLFILSWLPLWTLMMLSDYADLSPNELQIINIYIYPFAHWLAFGNSSVNPIIYGFFNENFRRGFQEAFQLQLCQKRAKPMEAYALKAKSHVLINTSNQLVQESTFQNPHGETLLYRKSAEKPQQELVMEELKETTNSSEI |
| UniProt | Q9Y5X5 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | N/A |
| 3D structure model | No available structures or models |
| BioLiP | N/A |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL5952 |
| IUPHAR | 301 |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 441757 |  CHEMBL3361427 | C22H36N6O | 400.571 | 4 / 4 | 2.7 | Yes |
| 441838 |  CHEMBL3361419 | C24H34N6O3 | 454.575 | 6 / 4 | 1.7 | Yes |
| 441917 |  CHEMBL3361412 | C35H52N6O5 | 636.838 | 8 / 4 | 6.5 | No |
| 442051 |  CHEMBL3360831 | C19H33N7O | 375.521 | 5 / 5 | -0.1 | Yes |
| 16896 |  CHEMBL574565 | C13H11F3N4O | 296.253 | 6 / 2 | 2.4 | Yes |
| 16898 |  CID 69536911 | C13H11F3N4O | 296.253 | 6 / 2 | 2.4 | Yes |
| 17312 |  CHEMBL2208340 | C22H28N6O3 | 424.505 | 4 / 5 | 0.5 | Yes |
| 17314 |  CHEMBL2204019 | C22H28N6O3 | 424.505 | 4 / 5 | 0.5 | Yes |
| 17316 |  CHEMBL2208339 | C22H28N6O3 | 424.505 | 4 / 5 | 0.5 | Yes |
| 21425 |  CHEMBL572825 | C15H18N4O | 270.336 | 3 / 2 | 2.7 | Yes |
| 442547 |  CHEMBL3361418 | C26H32N6O | 444.583 | 4 / 4 | 3.0 | Yes |
| 24522 |  CHEMBL2208309 | C19H28N6O5 | 420.47 | 6 / 6 | -1.7 | No |
| 555587 |  RFRP-1 | C64H96N18O12S | 1341.65 | 16 / 14 | 0.2 | No |
| 522372 |  CHEMBL3786583 | C76H104F9N19O23 | 1822.76 | 35 / 23 | N/A | No |
| 442789 |  CHEMBL3361420 | C23H32N6O2 | 424.549 | 5 / 4 | 1.7 | Yes |
| 35319 |  CHEMBL2208074 | C23H30N6O4 | 454.531 | 5 / 6 | 0.3 | No |
| 40229 |  CHEMBL2208297 | C30H33N7O3 | 539.64 | 4 / 6 | 2.8 | No |
| 46848 |  CHEMBL573738 | C13H14N4O | 242.282 | 3 / 2 | 1.9 | Yes |
| 49373 |  CHEMBL388586 | C41H51FN10O6 | 798.921 | 8 / 9 | 2.4 | No |
| 58066 |  CHEMBL2208295 | C26H30N6O3 | 474.565 | 4 / 5 | 1.9 | Yes |
| 523376 |  CHEMBL508974 | C32H38N6O6 | 602.692 | 7 / 6 | 3.4 | No |
| 63703 |  CHEMBL2208311 | C25H29N7O3 | 475.553 | 5 / 5 | 1.0 | Yes |
| 444352 |  CHEMBL3361414 | C37H48N6O5 | 656.828 | 8 / 4 | 7.5 | No |
| 444651 |  CHEMBL3361429 | C26H32N6O | 444.583 | 4 / 4 | 3.0 | Yes |
| 74583 |  CHEMBL2208076 | C24H30N6O4 | 466.542 | 5 / 6 | 0.8 | No |
| 76026 |  CHEMBL2208070 | C25H34N6O5 | 498.584 | 6 / 5 | 0.6 | Yes |
| 445505 |  CHEMBL3360836 | C20H27N5 | 337.471 | 3 / 3 | 2.3 | Yes |
| 97179 |  CHEMBL2208075 | C23H30N6O5 | 470.53 | 6 / 7 | -0.1 | No |
| 445633 |  CHEMBL3352907 | C34H50N6O5 | 622.811 | 8 / 4 | 6.1 | No |
| 111286 |  CHEMBL2208333 | C23H30N6O4 | 454.531 | 5 / 5 | 0.7 | Yes |
| 116678 |  CHEMBL2208308 | C21H33N7O3 | 431.541 | 5 / 6 | -1.1 | No |
| 117110 |  CHEMBL573519 | C14H14F3N5 | 309.296 | 5 / 2 | 2.1 | Yes |
| 117984 |  CHEMBL2208312 | C25H29N7O3 | 475.553 | 5 / 5 | 1.3 | Yes |
| 122296 |  CHEMBL2208080 | C26H36N6O3 | 480.613 | 4 / 5 | 2.4 | Yes |
| 478470 |  Neuropeptide FF | C54H76N14O10 | 1081.29 | 12 / 12 | -0.3 | No |
| 555980 |  AC1NQ0SC | C54H76N14O10 | 1081.29 | 12 / 12 | -0.3 | No |
| 137595 |  CHEMBL2208314 | C23H28N8O3 | 464.53 | 5 / 6 | 0.6 | No |
| 447248 |  CHEMBL3361424 | C24H33N5O | 407.562 | 3 / 3 | 2.6 | Yes |
| 141685 |  CHEMBL2208078 | C29H32N6O4 | 528.613 | 5 / 5 | 2.0 | No |
| 447587 |  CHEMBL3361436 | C29H35N5O | 469.633 | 3 / 3 | 3.9 | Yes |
| 150043 |  311309-27-0 | C45H72N14O10 | 969.159 | 12 / 11 | -2.5 | No |
| 525835 |  CHEMBL3786309 | C65H91N17O16 | 1366.55 | 18 / 18 | -3.9 | No |
| 151719 |  CHEMBL2208331 | C22H26Cl2N6O3 | 493.389 | 4 / 5 | 1.9 | Yes |
| 447749 |  CHEMBL3361434 | C23H29Cl2N5O | 462.419 | 3 / 3 | 3.5 | Yes |
| 447865 |  CHEMBL3361416 | C22H30N6O | 394.523 | 4 / 4 | 1.8 | Yes |
| 447878 |  CHEMBL3361421 | C22H28Cl2N6O | 463.407 | 4 / 4 | 3.0 | Yes |
| 157688 |  CHEMBL2165922 | C12H20N4 | 220.32 | 2 / 2 | 1.4 | Yes |
| 447999 |  CHEMBL3361423 | C23H31N5O | 393.535 | 3 / 3 | 2.3 | Yes |
| 161516 |  CHEMBL2208059 | C24H30N6O4 | 466.542 | 5 / 6 | 0.8 | No |
| 164511 |  CHEMBL2208073 | C23H30N6O4 | 454.531 | 5 / 6 | 0.3 | No |
| 170738 |  CHEMBL2208328 | C21H27N7O3 | 425.493 | 5 / 5 | -0.6 | Yes |
| 556172 |  BDBM50368404 | C112H174N36O27 | 2456.85 | 33 / 41 | -3.6 | No |
| 448720 |  CHEMBL3361417 | C23H32N6O | 408.55 | 4 / 4 | 1.2 | Yes |
| 448745 |  CHEMBL3360834 | C29H39N7O | 501.679 | 5 / 5 | 2.7 | No |
| 178862 |  BIBP3226 | C27H31N5O3 | 473.577 | 4 / 5 | 2.5 | Yes |
| 556188 |  CHEMBL44246 | C27H31N5O3 | 473.577 | 4 / 5 | 2.5 | Yes |
| 448763 |  CHEMBL3361435 | C27H33N5O | 443.595 | 3 / 3 | 3.5 | Yes |
| 183316 |  CHEMBL2208081 | C22H29N7O4 | 455.519 | 6 / 5 | -0.1 | Yes |
| 448964 |  CHEMBL3361415 | C38H50N6O5 | 670.855 | 8 / 4 | 7.4 | No |
| 192770 |  CHEMBL2208316 | C23H30N6O3 | 438.532 | 4 / 5 | 0.4 | Yes |
| 192773 |  SCHEMBL7535795 | C23H30N6O3 | 438.532 | 4 / 5 | 0.4 | Yes |
| 192774 |  CHEMBL2208317 | C23H30N6O3 | 438.532 | 4 / 5 | 0.4 | Yes |
| 198383 |  CHEMBL2208301 | C30H35N7O3S | 573.716 | 6 / 5 | 2.5 | No |
| 199223 |  CHEMBL2208327 | C21H27N7O3 | 425.493 | 5 / 5 | -0.4 | Yes |
| 449712 |  CHEMBL3361413 | C37H48N6O5 | 656.828 | 8 / 4 | 7.5 | No |
| 208507 |  CHEMBL573518 | C13H11F3N4S | 312.314 | 6 / 2 | 3.0 | Yes |
| 223183 |  CHEMBL1672379 | C40H64N12O11 | 889.025 | 13 / 12 | -5.0 | No |
| 227936 |  CHEMBL2208067 | C24H32N6O3 | 452.559 | 4 / 5 | 0.8 | Yes |
| 237558 |  SCHEMBL7560327 | C24H29N7O3 | 463.542 | 4 / 6 | 1.1 | No |
| 556416 |  PrRP24-31 | C42H67N13O9 | 898.08 | 11 / 10 | -1.8 | No |
| 244312 |  CHEMBL2208320 | C28H32N6O3 | 500.603 | 4 / 5 | 2.3 | No |
| 244313 |  CHEMBL2208338 | C28H32N6O3 | 500.603 | 4 / 5 | 2.3 | No |
| 244316 |  CHEMBL2208337 | C28H32N6O3 | 500.603 | 4 / 5 | 2.3 | No |
| 451355 |  CHEMBL3361410 | C23H32N6O | 408.55 | 4 / 4 | 1.5 | Yes |
| 249091 |  SCHEMBL7528463 | C22H27ClN6O3 | 458.947 | 4 / 5 | 1.3 | Yes |
| 252534 |  Peptide analogue, 19 | C42H52FN9O5 | 781.934 | 7 / 8 | 3.4 | No |
| 256198 |  CHEMBL2208065 | C26H44N6O3 | 488.677 | 4 / 5 | 3.4 | Yes |
| 257770 |  CHEMBL2208062 | C23H29N7O3 | 451.531 | 5 / 5 | 0.0 | Yes |
| 265080 |  CHEMBL2208323 | C28H32N6O3 | 500.603 | 4 / 5 | 2.3 | No |
| 265083 |  CHEMBL2208322 | C28H32N6O3 | 500.603 | 4 / 5 | 2.3 | No |
| 265085 |  CHEMBL2208321 | C28H32N6O3 | 500.603 | 4 / 5 | 2.3 | No |
| 452481 |  CHEMBL3361428 | C23H32N6O | 408.55 | 4 / 4 | 2.2 | Yes |
| 277784 |  CHEMBL2208298 | C23H28N8O3 | 464.53 | 5 / 6 | 0.2 | No |
| 278622 |  CHEMBL2208299 | C29H34N6O3 | 514.63 | 4 / 5 | 2.3 | No |
| 278623 |  CHEMBL2208319 | C29H34N6O3 | 514.63 | 4 / 5 | 2.3 | No |
| 278625 |  CHEMBL2208318 | C29H34N6O3 | 514.63 | 4 / 5 | 2.3 | No |
| 279330 |  AC1MCKWV | C8H8Cl2N4 | 231.08 | 2 / 2 | 1.9 | Yes |
| 279332 |  CHEMBL572531 | C8H8Cl2N4 | 231.08 | 2 / 2 | 1.9 | Yes |
| 287583 |  CHEMBL2208332 | C22H26Cl2N6O3 | 493.389 | 4 / 5 | 1.9 | Yes |
| 453143 |  CHEMBL3361426 | C15H24N6O | 304.398 | 4 / 5 | -0.2 | Yes |
| 453155 |  CHEMBL3361431 | C22H29BrN6O | 473.419 | 4 / 4 | 2.5 | Yes |
| 292882 |  CHEMBL574353 | C10H10ClF3N4 | 278.663 | 5 / 2 | 2.2 | Yes |
| 294347 |  CHEMBL2208304 | C24H30N6O3 | 450.543 | 4 / 5 | 1.1 | Yes |
| 294349 |  CHEMBL2208303 | C24H30N6O3 | 450.543 | 4 / 5 | 1.1 | Yes |
| 294350 |  CHEMBL2208302 | C24H30N6O3 | 450.543 | 4 / 5 | 1.1 | Yes |
| 294772 |  CHEMBL2208066 | C20H32N6O3 | 404.515 | 4 / 5 | 0.2 | Yes |
| 295016 |  CHEMBL2208326 | C28H32N6O3 | 500.603 | 4 / 5 | 2.3 | No |
| 295019 |  CHEMBL2208325 | C28H32N6O3 | 500.603 | 4 / 5 | 2.3 | No |
| 295021 |  CHEMBL2208324 | C28H32N6O3 | 500.603 | 4 / 5 | 2.3 | No |
| 453414 |  CHEMBL3361433 | C27H33N5O | 443.595 | 3 / 3 | 3.5 | Yes |
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