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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL504861
Molecular formula	C34H31FN4O4
IUPAC name	3-[4-[1-(3-ethoxyphenyl)-2-(2-fluoro-4-methylphenyl)imidazole-4-carbonyl]piperazin-1-yl]naphthalene-1-carboxylic acid
Molecular weight	578.644
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	6.3
Synonyms	BDBM50245187 SCHEMBL502739 3-(4-(1-(3-ethoxyphenyl)-2-(2-fluoro-4-methylphenyl)-1H-imidazole-4-carbonyl)piperazin-1-yl)-1-naphthoic acid
Inchi Key	AACZCKZTUMTPKO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C34H31FN4O4/c1-3-43-26-9-6-8-24(19-26)39-21-31(36-32(39)28-12-11-22(2)17-30(28)35)33(40)38-15-13-37(14-16-38)25-18-23-7-4-5-10-27(23)29(20-25)34(41)42/h4-12,17-21H,3,13-16H2,1-2H3,(H,41,42)
PubChem CID	24861060
ChEMBL	CHEMBL504861
IUPHAR	N/A
BindingDB	50245187
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
72	Cholecystokinin receptor type A	O08786	Cckar	Mus musculus (Mouse)	436
73	Cholecystokinin receptor type A	P32238	CCKAR	Homo sapiens (Human)	428
74	Gastrin/cholecystokinin type B receptor	P32239	CCKBR	Homo sapiens (Human)	447
75	Gastrin/cholecystokinin type B receptor	P56481	Cckbr	Mus musculus (Mouse)	453

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