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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	2-{3-[4-(2-methoxyphenyl)-1-piperazinyl]propyl}tetrahydro-1H-pyrrolo[1,2-c]imidazole-1,3(2H)-dione
Molecular formula	C20H28N4O3
IUPAC name	2-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]-5,6,7,7a-tetrahydropyrrolo[1,2-c]imidazole-1,3-dione
Molecular weight	372.469
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	1.8
Synonyms	AC1N52R2 MCULE-1619189230 2-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]-5,6,7,7a-tetrahydropyrrolo[1,2-c]imidazole-1,3-dione SMR000477701 AP-685/41280878 MLS001182582 Tetrahydro-2-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]-1H-pyrrolo[1,2-c]imidazole-1,3(2H)-dione MolPort-002-845-803 [ Show all ]
Inchi Key	AAKOYVKAXOHXBZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H28N4O3/c1-27-18-8-3-2-6-16(18)22-14-12-21(13-15-22)9-5-11-24-19(25)17-7-4-10-23(17)20(24)26/h2-3,6,8,17H,4-5,7,9-15H2,1H3
PubChem CID	4188516
ChEMBL	CHEMBL289873
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
275	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
276	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
274	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444

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