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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL199111
Molecular formula	C24H31N3O5S
IUPAC name	N-[(1S)-2-[(3S)-3-hydroxypyrrolidin-1-yl]-1-phenylethyl]-N-methyl-6-(methylsulfamoyl)-3,4-dihydro-2H-chromene-2-carboxamide
Molecular weight	473.588
Hydrogen bond acceptor	7
Hydrogen bond donor	2
XlogP	1.9
Synonyms	6-Methylsulfamoyl-chroman-2-carboxylic acid [(S)-2-((S)-3-hydroxy-pyrrolidin-1-yl)-1-phenyl-ethyl]-methyl-amide BDBM50174966
Inchi Key	ACGXEHCYMVMMDU-ZPVUCFGCSA-N
Inchi ID	InChI=1S/C24H31N3O5S/c1-25-33(30,31)20-9-11-22-18(14-20)8-10-23(32-22)24(29)26(2)21(17-6-4-3-5-7-17)16-27-13-12-19(28)15-27/h3-7,9,11,14,19,21,23,25,28H,8,10,12-13,15-16H2,1-2H3/t19-,21+,23?/m0/s1
PubChem CID	44405161
ChEMBL	CHEMBL199111
IUPHAR	N/A
BindingDB	50174966
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
1566	Kappa-type opioid receptor	P41145	OPRK1	Homo sapiens (Human)	380
1565	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400

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