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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000587548
Molecular formula	C24H22Cl2N2O2
IUPAC name	(7E)-2-amino-4-(2-chlorophenyl)-7-[(2-chlorophenyl)methylidene]-5,6-dihydro-4H-cyclopenta[b]pyran-3-carbonitrile;ethanol
Molecular weight	441.352
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	None
Synonyms	SMR000211567 AKOS024302050 HMS2612N09 2-Amino-4-(2-chloro-phenyl)-7-[1-(2-chloro-phenyl)-meth-(E)-ylidene]-4,5,6,7-tetrahydro-cyclopenta[b]pyran-3-carbonitrile CHEMBL1537070
Inchi Key	ADCNYPCMZJMRFF-JHGYPSGKSA-N
Inchi ID	InChI=1S/C22H16Cl2N2O.C2H6O/c23-18-7-3-1-5-13(18)11-14-9-10-16-20(15-6-2-4-8-19(15)24)17(12-25)22(26)27-21(14)16;1-2-3/h1-8,11,20H,9-10,26H2;3H,2H2,1H3/b14-11+;
PubChem CID	12005524
ChEMBL	CHEMBL1537070
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	Partition coefficient log P of this ligand is not available.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
2127	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
2126	Neuropeptide S receptor	Q6W5P4	NPSR1	Homo sapiens (Human)	371
463197	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593

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