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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	8-(3,4-dimethoxyphenyl)-3-(4-fluorophenyl)-2-methyl-8,9-dihydropyrazolo[1,5-a]quinazolin-6(7H)-one
Molecular formula	C25H22FN3O3
IUPAC name	8-(3,4-dimethoxyphenyl)-3-(4-fluorophenyl)-2-methyl-8,9-dihydro-7H-pyrazolo[1,5-a]quinazolin-6-one
Molecular weight	431.467
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	3.9
Synonyms	AKOS016159112 NCGC00103163-01 8-(3,4-dimethoxyphenyl)-3-(4-fluorophenyl)-2-methyl-8,9-dihydro-7H-pyrazolo[1,5-a]quinazolin-6-one CHEMBL1316500 AC1MKT7K MCULE-5421601694 BAS 12534556 ST50293505 HMS1809K10 AKOS000629629 MolPort-000-410-868 8-(3,4-dimethoxyphenyl)-3-(4-fluorophenyl)-2-methyl-7,8,9,10-tetrahydropyrazol o[1,5-a]quinazolin-6-one STK231415 876668-13-2 HMS3431H06 [ Show all ]
Inchi Key	ADPUTCZLQJJHFX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H22FN3O3/c1-14-24(15-4-7-18(26)8-5-15)25-27-13-19-20(29(25)28-14)10-17(11-21(19)30)16-6-9-22(31-2)23(12-16)32-3/h4-9,12-13,17H,10-11H2,1-3H3
PubChem CID	3162808
ChEMBL	CHEMBL1316500
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
2946	Relaxin receptor 1	Q9HBX9	RXFP1	Homo sapiens (Human)	757

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