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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL127463
Molecular formula	C25H24FN3O
IUPAC name	4-fluoro-N-[2-(1-methyl-5-phenyl-2,3-dihydro-1,4-benzodiazepin-2-yl)ethyl]benzamide
Molecular weight	401.485
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	4.7
Synonyms	va-100 BDBM50049802 N-[2-[(2,3-Dihydro-1-methyl-5-phenyl-1H-1,4-benzodiazepin)-2-yl]ethyl]-4-fluorobenzamide 4-Fluoro-N-[2-(1-methyl-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-2-yl)-ethyl]-benzamide SCHEMBL719208
Inchi Key	AESATWJIMVTHFR-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H24FN3O/c1-29-21(15-16-27-25(30)19-11-13-20(26)14-12-19)17-28-24(18-7-3-2-4-8-18)22-9-5-6-10-23(22)29/h2-14,21H,15-17H2,1H3,(H,27,30)
PubChem CID	10408752
ChEMBL	CHEMBL127463
IUPHAR	N/A
BindingDB	50049802
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
3799	Delta-type opioid receptor	P41143	OPRD1	Homo sapiens (Human)	372
3801	Kappa-type opioid receptor	P41145	OPRK1	Homo sapiens (Human)	380
3802	Kappa-type opioid receptor	P41144	OPRK1	Cavia porcellus (Guinea pig)	380
3800	Mu-type opioid receptor	P97266	OPRM1	Cavia porcellus (Guinea pig)	98

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