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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL285712
Molecular formula	C24H25FN2O
IUPAC name	5-(9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl)-1-(4-fluorophenyl)pentan-1-one
Molecular weight	376.475
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	4.7
Synonyms	SCHEMBL466781 5-[9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-1-(4-fluorophenyl)-1-pentanone (7R,10S)-5-[9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-1-(4-fluorophenyl)-1-pentanone (7S,10R)-5-[9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-1-(4-fluorophenyl)-1-pentanone BDBM50036647
Inchi Key	AFVUFWHJUYVTQW-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H25FN2O/c25-17-10-8-16(9-11-17)23(28)7-3-4-14-27-18-12-13-22(27)24-19-5-1-2-6-20(19)26-21(24)15-18/h1-2,5-6,8-11,18,22,26H,3-4,7,12-15H2
PubChem CID	9842628
ChEMBL	CHEMBL285712
IUPHAR	N/A
BindingDB	50036647
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
4543	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
4544	D(2) dopamine receptor	P61168	Drd2	Mus musculus (Mouse)	444

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