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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N'-[(E)-(4-hydroxy-3-methoxyphenyl)methylidene]acetohydrazide
Molecular formula	C17H18N6O5
IUPAC name	2-(1,3-dimethyl-2,6-dioxopurin-7-yl)-N-[(E)-(4-hydroxy-3-methoxyphenyl)methylideneamino]acetamide
Molecular weight	386.368
Hydrogen bond acceptor	7
Hydrogen bond donor	2
XlogP	0.2
Synonyms	AKOS002175031 STK036928 2-(1,3-dimethyl-2,6-dioxopurin-7-yl)-N'-[(3-methoxy-4-oxocyclohexa-2,5-dien-1-ylidene)methyl]acetohydrazide MLS000778128 AC1NZSYY SMR000414522 (1,3-Dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-purin-7-yl)-acetic acid [1-(4-hydroxy-3-methoxy-phenyl)-meth-(E)-ylidene]-hydrazide 2-(1,3-dimethyl-2,6-dioxopurin-7-yl)-N'-[(E)-(3-methoxy-4-oxocyclohexa-2,5-dien-1-ylidene)methyl]acetohydrazide MolPort-000-442-962 AC1OAGNS ST50061607 CHEMBL1979668 374677-44-8 N-[(1E)-2-(4-hydroxy-3-methoxyphenyl)-1-azavinyl]-2-(1,3-dimethyl-2,6-dioxo(1, 3,7-trihydropurin-7-yl))acetamide [ Show all ]
Inchi Key	ALUYWDYRWYPVTP-FBCYGCLPSA-N
Inchi ID	InChI=1S/C17H18N6O5/c1-21-15-14(16(26)22(2)17(21)27)23(9-18-15)8-13(25)20-19-7-10-4-5-11(24)12(6-10)28-3/h4-7,9,24H,8H2,1-3H3,(H,20,25)/b19-7+
PubChem CID	135641876
ChEMBL	CHEMBL1979668
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
557518	Relaxin receptor 1	Q9HBX9	RXFP1	Homo sapiens (Human)	757
557516	Relaxin receptor 2	Q8WXD0	RXFP2	Homo sapiens (Human)	754
557517	Vasopressin V1b receptor	P47901	AVPR1B	Homo sapiens (Human)	424

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