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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL136684
Molecular formula	C19H20N4O2
IUPAC name	2-(3,4-dihydro-1H-isoquinolin-2-yl)-6,7-dimethoxyquinazolin-4-amine
Molecular weight	336.395
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	3.1
Synonyms	2-(3,4-Dihydro-1H-isoquinolin-2-yl)-6,7-dimethoxy-quinazolin-4-ylamine BDBM50073575 SR-01000651481 2-[3,4-Dihydroisoquinoline-2(1H)-yl]-6,7-dimethoxyquinazoline-4-amine SR-01000651481-1
Inchi Key	AMHBGRVKWJLMMP-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H20N4O2/c1-24-16-9-14-15(10-17(16)25-2)21-19(22-18(14)20)23-8-7-12-5-3-4-6-13(12)11-23/h3-6,9-10H,7-8,11H2,1-2H3,(H2,20,21,22)
PubChem CID	10664606
ChEMBL	CHEMBL136684
IUPHAR	N/A
BindingDB	50073575
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
8879	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
8878	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
8880	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444

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