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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL418678
Molecular formula	C20H19FN4S
IUPAC name	8-[4-[(4-fluorophenyl)methyl]piperazin-1-yl]-3-thia-1,7-diazatricyclo[7.3.0.02,6]dodeca-2(6),4,7,9,11-pentaene
Molecular weight	366.458
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	4.7
Synonyms	5-[4-(4-Fluorobenzyl)-1-piperazinyl]pyrrolo[1,2-a]thieno[3,2-e]pyrazine BDBM50407772
Inchi Key	ANJGZJUIHVVPCI-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H19FN4S/c21-16-5-3-15(4-6-16)14-23-9-11-24(12-10-23)19-18-2-1-8-25(18)20-17(22-19)7-13-26-20/h1-8,13H,9-12,14H2
PubChem CID	11793287
ChEMBL	CHEMBL418678
IUPHAR	N/A
BindingDB	50407772
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
9617	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
9616	5-hydroxytryptamine receptor 1B	P28564	Htr1b	Rattus norvegicus (Rat)	386
9613	5-hydroxytryptamine receptor 1D	P79400	HTR1D	Sus scrofa (Pig)	291
9614	5-hydroxytryptamine receptor 2A	Q75Z89	HTR2A	Bos taurus (Bovine)	470
9615	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458

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