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Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
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Ligand

Name	tryptamine
Molecular formula	C10H12N2
IUPAC name	2-(1H-indol-3-yl)ethanamine
Molecular weight	160.22
Hydrogen bond acceptor	1
Hydrogen bond donor	2
XlogP	1.6
Synonyms	SBB003963 beta-(3-Indolyl)ethylamine Spectrum2_000873 CCG-40088 ST50308344 DB-005731 (3-Indolyl)ethylamine FS-3317 2-(1h-indol-3-yl) ethylamine HY-B2132 2-(3-Indolyl)ethylamine; 3-(2-Aminoethyl)indole KBio2_002961 3-Indoleethanamine Lopac0_000061 NCGC00014994-02 ACN-000556 NCGC00095081-03 AM807158 TRA0076983 tryptaminium SCHEMBL26725 BR-80344 Spectrum5_001296 DTXSID2075340 GTPL125 2-(1H-Indol-3-Yl)Ethan-1-Amine Indol-3-ethylamine 2-indol-3-yl-ethylamine KBioGR_001459 3-[2-Aminoethyl]indole MCULE-6402431765 AB0007015 NCGC00014994-05 ACT09907 NINDS_000862 APJYDQYYACXCRM-UHFFFAOYSA-N VI30132 BCP21605 SPBio_000945 BSPBio_003400 SR-01000075589-5 CTK2F4020 EINECS 200-510-5 HMS502L04 2-(1H-indol-3-yl)ethylamine KBio1_000862 3-(2-aminoethyl)indole L000946 422ZU9N5TV MolPort-001-002-280 AC1Q54C3 NCGC00095081-01 AKOS000119468 RP22361 Tryptamine, free base T0890 SC-05762 bmse000207 Spectrum3_001890 CCRIS 8959 STK262895 DB08653 (Amino-2 ethyl)-3 indole FT-0081340 2-(1H-indol-3-yl)-ethyl-amine IDI1_000862 2-(Indol-3-yl)ethylamine KBio2_005529 3-Indoleethylamine LS-82268 5E7B376B-5933-446C-9D88-661B5F480122 NCGC00014994-03 ACN-036699 NCGC00095081-04 AN-41829 triptamine UNII-422ZU9N5TV SDCCGMLS-0066798.P001 BRD-K44218819-001-05-1 Spectrum_000033 CHEMBL6640 EBD10651 .beta.-(3-Indolyl)ethylamine HMS1922K18 2-(1H-Indol-3-yl)ethanamine Indole, 3-(2-aminoethyl)- 2-Indol-3-ylethylamine KBioSS_000393 343-94-2 (mono-hydrochloride) MFCD00005661 AB1001199 NCGC00014994-06 AE-848/30735051 Oprea1_870097 AZ0001-0257 Tryptamine, 98% ZINC120144 BDBM50024210 SPECTRUM1503922 C00398 ST2409261 D08CJK F2169-0960 1H-Indole-3-ethanamine HTS028111 2-(3-Indolyl)ethylamine KBio2_000393 3-(beta-aminoethyl)-indole Lopac-246557 5-22-10-00045 (Beilstein Handbook Reference) NCGC00014994-01 ACMC-209mtp NCGC00095081-02 ALBB-017957 RTC-066345 Tryptamine, Vetec(TM) reagent grade, 98% TC-066345 SCHEMBL13006684 BP-12561 Spectrum4_000850 CHEBI:16765 T-8095 DivK1c_000862 (Amino-2 ethyl)-3 indole [French] FT-0613523 2-(1H-INDOL-3-YL)-ETHYLAMINE InChI=1/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H 2-Indol-3-yl-aethylamin KBio3_002903 3-indolylethylamine M-3012 61-54-1 NCGC00014994-04 ACN-F000556 NCGC00095081-05 ANW-33851 Tryptamin V2315 BBL015353 SMR000112268 BRN 0125513 SR-01000075589 CS-D1750 EC 200-510-5 005T661 HMS2267B18 2-(1H-Indol-3-yl)ethanamine # KB-81364 3-(2-amino)ethyl indole KSC354A2B 34685-69-3 (unspecified sulfate) MLS000515794 AC1L1AU8 NCGC00014994-07 AJ-11665 PubChem9450 Tryptamine, analytical standard [2-(1h-indol-3-yl)ethyl]amine T-8100 [ Show all ]
Inchi Key	APJYDQYYACXCRM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H2
PubChem CID	1150
ChEMBL	CHEMBL6640
IUPHAR	125
BindingDB	50024210
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
11053	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
11067	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
11056	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
11072	5-hydroxytryptamine receptor 1B	P28564	Htr1b	Rattus norvegicus (Rat)	386
11052	5-hydroxytryptamine receptor 1D	P79400	HTR1D	Sus scrofa (Pig)	291
11062	5-hydroxytryptamine receptor 1D	P28221	HTR1D	Homo sapiens (Human)	377
11071	5-hydroxytryptamine receptor 1D	P11614	HTR1D	Canis lupus familiaris (Dog)	377
11068	5-hydroxytryptamine receptor 1E	P28566	HTR1E	Homo sapiens (Human)	365
11063	5-hydroxytryptamine receptor 1F	P30939	HTR1F	Homo sapiens (Human)	366
11065	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
11069	5-hydroxytryptamine receptor 2A	P50129	HTR2A	Sus scrofa (Pig)	470
553303	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
11057	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
11060	5-hydroxytryptamine receptor 2B	P30994	Htr2b	Rattus norvegicus (Rat)	479
555520	5-hydroxytryptamine receptor 2B	Q02152	Htr2b	Mus musculus (Mouse)	479
11055	5-hydroxytryptamine receptor 2C	P08909	Htr2c	Rattus norvegicus (Rat)	460
11059	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
555521	5-hydroxytryptamine receptor 4	P97288	Htr4	Mus musculus (Mouse)	388
11058	5-hydroxytryptamine receptor 6	P31388	Htr6	Rattus norvegicus (Rat)	436
11070	5-hydroxytryptamine receptor 6	P50406	HTR6	Homo sapiens (Human)	440