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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000106678
Molecular formula	C11H12N2OS
IUPAC name	4-methoxy-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidine
Molecular weight	220.29
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	3.1
Synonyms	4-Methoxy-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidine AC1LETCG F0239-0404 SMR000111055 4-methoxy-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidine BDBM49117 HMS552F05 ST50023196 40277-31-4 CHEMBL1423515 ZINC116423 4-methoxy-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidine AKOS000281631 HMS2449E06 SR-01000392419 4-methoxy-5,6,7,8-tetrahydrobenzo[b]thiopheno[2,3-d]pyrimidine CCG-240383 Maybridge1_003811 STK394315 3-methoxy-8-thia-4,6-diazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2,4,6-tetraene cid_717679 MolPort-000-703-649 4-methoxy-5,6,7,8-tetrahydrobenzothiopheno[2,3-d]pyrimidine BAS 06105288 HMS3437C05 SR-01000392419-1 4-methoxy-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidine MCULE-4901961585 Z31131451 [ Show all ]
Inchi Key	APMNRWQWJSNFBB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C11H12N2OS/c1-14-10-9-7-4-2-3-5-8(7)15-11(9)13-6-12-10/h6H,2-5H2,1H3
PubChem CID	717679
ChEMBL	CHEMBL1423515
IUPHAR	N/A
BindingDB	49117
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
11128	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
464242	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593

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