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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL143944
Molecular formula	C21H24FN3O3S
IUPAC name	7-[3-[4-(4-fluorophenyl)piperazin-1-yl]-2-hydroxypropoxy]-4H-1,4-benzothiazin-3-one
Molecular weight	417.499
Hydrogen bond acceptor	7
Hydrogen bond donor	2
XlogP	2.5
Synonyms	7-{3-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-2-hydroxy-propoxy}-4H-benzo[1,4]thiazin-3-one BDBM50086665 7-[2-Hydroxy-3-[4-(4-fluorophenyl)piperazino]propoxy]-3,4-dihydro-2H-1,4-benzothiazine-3-one
Inchi Key	ASDLXXUOHBNMMC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H24FN3O3S/c22-15-1-3-16(4-2-15)25-9-7-24(8-10-25)12-17(26)13-28-18-5-6-19-20(11-18)29-14-21(27)23-19/h1-6,11,17,26H,7-10,12-14H2,(H,23,27)
PubChem CID	44361776
ChEMBL	CHEMBL143944
IUPHAR	N/A
BindingDB	50086665
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
13029	Beta-1 adrenergic receptor	P18090	Adrb1	Rattus norvegicus (Rat)	466
13030	Beta-2 adrenergic receptor	P54833	ADRB2	Canis lupus familiaris (Dog)	415

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