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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000570445
Molecular formula	C25H20N2O3
IUPAC name	N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-(4-methylphenyl)quinoline-4-carboxamide
Molecular weight	396.446
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	4.8
Synonyms	cid_1220296 N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-(p-tolyl)cinchoninamide AC1LOGHU MCULE-7495958112 SMR000186872 N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-(4-methylphenyl)-4-quinolinecarboxamide HMS2165E20 Oprea1_115051 AKOS003252295 STK418964 CHEMBL1499276 N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-(4-methylphenyl)quinoline-4-carboxamide HMS3319M15 REGID_for_CID_1220296 BDBM42522 MolPort-001-490-244 ZINC995297 [ Show all ]
Inchi Key	AVBFGEPJASDZCA-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H20N2O3/c1-16-6-8-17(9-7-16)22-15-20(19-4-2-3-5-21(19)27-22)25(28)26-18-10-11-23-24(14-18)30-13-12-29-23/h2-11,14-15H,12-13H2,1H3,(H,26,28)
PubChem CID	1220296
ChEMBL	CHEMBL1499276
IUPHAR	N/A
BindingDB	42522
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
15151	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
15150	Neuropeptide Y receptor type 1	P25929	NPY1R	Homo sapiens (Human)	384
15149	Neuropeptide Y receptor type 2	P49146	NPY2R	Homo sapiens (Human)	381

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