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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL606343
Molecular formula	C27H28N2O5
IUPAC name	(1R,2S,6R,14R,15S,19R)-11,15-dimethoxy-5-methyl-19-(4-nitrophenyl)-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11,16-tetraene
Molecular weight	460.53
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	3.9
Synonyms	BDBM50305088 22-nitro-7apha-phenyl-6alpha,14alpha-endo-Ethenotetrahydrothebaine
Inchi Key	AWNRNVHRUCSKRX-FGYBOQAASA-N
Inchi ID	InChI=1S/C27H28N2O5/c1-28-13-12-26-22-17-6-9-20(32-2)23(22)34-24(26)27(33-3)11-10-25(26,21(28)14-17)15-19(27)16-4-7-18(8-5-16)29(30)31/h4-11,19,21,24H,12-15H2,1-3H3/t19-,21-,24-,25-,26+,27+/m1/s1
PubChem CID	46227748
ChEMBL	CHEMBL606343
IUPHAR	N/A
BindingDB	50305088
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
16197	Delta-type opioid receptor	P33533	Oprd1	Rattus norvegicus (Rat)	372
16198	Kappa-type opioid receptor	P41145	OPRK1	Homo sapiens (Human)	380
16196	Mu-type opioid receptor	P33535	Oprm1	Rattus norvegicus (Rat)	398

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