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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL597702
Molecular formula	C31H29ClF2N2O
IUPAC name	(5R)-5-[4-[(N-benzyl-2,4-difluoroanilino)methyl]phenyl]-8-chloro-3-methyl-1,2,4,5-tetrahydro-3-benzazepin-7-ol
Molecular weight	519.033
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	7.3
Synonyms	BDBM50306319 (R)-5-(4-((benzyl(2,4-difluorophenyl)amino)methyl)phenyl)-8-chloro-3-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol
Inchi Key	AWUWWSPJQVWBIM-HHHXNRCGSA-N
Inchi ID	InChI=1S/C31H29ClF2N2O/c1-35-14-13-24-15-28(32)31(37)17-26(24)27(20-35)23-9-7-22(8-10-23)19-36(18-21-5-3-2-4-6-21)30-12-11-25(33)16-29(30)34/h2-12,15-17,27,37H,13-14,18-20H2,1H3/t27-/m1/s1
PubChem CID	46231645
ChEMBL	CHEMBL597702
IUPHAR	N/A
BindingDB	50306319
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
16386	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
16387	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443

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