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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SCHEMBL1276324
Molecular formula	C24H26F2N4O2
IUPAC name	4-(2,4-difluoroanilino)-7-ethoxy-6-(1-methylpiperidin-4-yl)quinoline-3-carboxamide
Molecular weight	440.495
Hydrogen bond acceptor	7
Hydrogen bond donor	2
XlogP	4.3
Synonyms	CHEMBL2409309
Inchi Key	AYGOUVZBEXIJRN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H26F2N4O2/c1-3-32-22-12-21-17(11-16(22)14-6-8-30(2)9-7-14)23(18(13-28-21)24(27)31)29-20-5-4-15(25)10-19(20)26/h4-5,10-14H,3,6-9H2,1-2H3,(H2,27,31)(H,28,29)
PubChem CID	24795066
ChEMBL	CHEMBL2409309
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
17450	Alpha-1A adrenergic receptor	P35348	ADRA1A	Homo sapiens (Human)	466
17451	Alpha-1D adrenergic receptor	P25100	ADRA1D	Homo sapiens (Human)	572
17449	Alpha-2A adrenergic receptor	P08913	ADRA2A	Homo sapiens (Human)	450

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