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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL134519
Molecular formula	C11H16INO2
IUPAC name	(2R)-1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine
Molecular weight	321.158
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	2.5
Synonyms	(r)-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane AJ-36945 Lopac0_000478 (R)-2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylamine CCG-204569 PDSP2_001372 (-)-DOI D01TSX ZINC2516053 (R)-1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine BDBM50133231 NCGC00162167-01 (R)-DOI R-DOI (2R)-1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine 82864-06-0 GTPL157 (R)-2-(4-Iodo-2,5-dimethoxy-phenyl)-1-methyl-ethylamine Benzeneethanamine, 4-iodo-2,5-dimethoxy-alpha-methyl-, (alphaR)- PDSP1_001388 SCHEMBL713061 [ Show all ]
Inchi Key	BGMZUEKZENQUJY-SSDOTTSWSA-N
Inchi ID	InChI=1S/C11H16INO2/c1-7(13)4-8-5-11(15-3)9(12)6-10(8)14-2/h5-7H,4,13H2,1-3H3/t7-/m1/s1
PubChem CID	9840090
ChEMBL	CHEMBL134519
IUPHAR	157
BindingDB	50133231
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
23158	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
23157	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
23160	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
23156	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
23159	5-hydroxytryptamine receptor 2B	P30994	Htr2b	Rattus norvegicus (Rat)	479
23161	5-hydroxytryptamine receptor 2C	P08909	Htr2c	Rattus norvegicus (Rat)	460
23162	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458

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