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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2181168
Molecular formula	C21H24IN3O
IUPAC name	7-iodo-5-[(1-propylpiperidin-4-yl)methoxy]benzo[h][1,6]naphthyridine
Molecular weight	461.347
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	5.1
Synonyms	BDBM50399622
Inchi Key	BIAZRDQNRJRCRQ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H24IN3O/c1-2-11-25-12-8-15(9-13-25)14-26-21-17-6-4-10-23-19(17)16-5-3-7-18(22)20(16)24-21/h3-7,10,15H,2,8-9,11-14H2,1H3
PubChem CID	71457409
ChEMBL	CHEMBL2181168
IUPHAR	N/A
BindingDB	50399622
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
24284	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
24289	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
24288	5-hydroxytryptamine receptor 1D	P28221	HTR1D	Homo sapiens (Human)	377
24283	5-hydroxytryptamine receptor 1E	P28566	HTR1E	Homo sapiens (Human)	365
24293	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
24291	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
24286	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
24282	5-hydroxytryptamine receptor 4	Q13639	HTR4	Homo sapiens (Human)	388
24285	5-hydroxytryptamine receptor 4	O70528	HTR4	Cavia porcellus (Guinea pig)	388
24292	5-hydroxytryptamine receptor 5A	P47898	HTR5A	Homo sapiens (Human)	357
24290	5-hydroxytryptamine receptor 6	P50406	HTR6	Homo sapiens (Human)	440
24287	5-hydroxytryptamine receptor 7	P34969	HTR7	Homo sapiens (Human)	479

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