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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL165350
Molecular formula	C22H20BrN3O2
IUPAC name	7-bromo-3-[2-(3,4-dihydro-1H-[1]benzofuro[3,2-c]pyridin-2-yl)ethyl]-2-methylpyrido[1,2-a]pyrimidin-4-one
Molecular weight	438.325
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	3.2
Synonyms	BDBM50403740 2-Methyl-3-[2-(1,2,3,4-tetrahydrobenzofuro[3,2-c]pyridine-2-yl)ethyl]-7-bromo-4H-pyrido[1,2-a]pyrimidine-4-one
Inchi Key	BRKWIMBSEICBCU-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H20BrN3O2/c1-14-16(22(27)26-12-15(23)6-7-21(26)24-14)8-10-25-11-9-20-18(13-25)17-4-2-3-5-19(17)28-20/h2-7,12H,8-11,13H2,1H3
PubChem CID	44377200
ChEMBL	CHEMBL165350
IUPHAR	N/A
BindingDB	50403740
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
31086	Alpha-1A adrenergic receptor	P35348	ADRA1A	Homo sapiens (Human)	466
31087	Alpha-2A adrenergic receptor	P08913	ADRA2A	Homo sapiens (Human)	450
31084	Alpha-2B adrenergic receptor	P18089	ADRA2B	Homo sapiens (Human)	450
31085	Alpha-2C adrenergic receptor	P18825	ADRA2C	Homo sapiens (Human)	462

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