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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000105277
Molecular formula	C17H22N4O2
IUPAC name	2-[4-[(2,4-dimethoxyphenyl)methyl]piperazin-1-yl]pyrimidine
Molecular weight	314.389
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	1.9
Synonyms	SMR000102158 2-[4-[(2,4-dimethoxyphenyl)methyl]piperazin-1-yl]pyrimidine HMS2426M23 ZINC19536698 BDBM38696 Oprea1_183822 2-[4-(2,4-dimethoxybenzyl)piperazino]pyrimidine CHEMBL1406964 SR-01000625602 Cambridge id 5262276 REGID_for_CID_199200 2-[4-[(2,4-dimethoxyphenyl)methyl]-1-piperazinyl]pyrimidine cid_199200 SR-01000625602-2 AC1L56WG MolPort-003-180-334 [ Show all ]
Inchi Key	CDJMANXRRPUKJG-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H22N4O2/c1-22-15-5-4-14(16(12-15)23-2)13-20-8-10-21(11-9-20)17-18-6-3-7-19-17/h3-7,12H,8-11,13H2,1-2H3
PubChem CID	199200
ChEMBL	CHEMBL1406964
IUPHAR	N/A
BindingDB	38696
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
39336	5-hydroxytryptamine receptor 2A	P35363	Htr2a	Mus musculus (Mouse)	471
467754	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
39335	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400

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