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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL420475
Molecular formula	C18H24N4O
IUPAC name	N-[3-(1-methylpiperidin-4-yl)-1H-pyrrolo[3,2-b]pyridin-5-yl]cyclobutanecarboxamide
Molecular weight	312.417
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	2.2
Synonyms	SCHEMBL7014587 BDBM50130433 5-(N-[cyclobutanecarbonyl]amino)-3-(1-methylpiperidin-4-yl)pyrrolo[3,2-b]pyridine CGNOEAKWDFGWNP-UHFFFAOYSA-N Cyclobutanecarboxylic acid [3-(1-methyl-piperidin-4-yl)-1H-pyrrolo[3,2-b]pyridin-5-yl]-amide
Inchi Key	CGNOEAKWDFGWNP-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H24N4O/c1-22-9-7-12(8-10-22)14-11-19-15-5-6-16(20-17(14)15)21-18(23)13-3-2-4-13/h5-6,11-13,19H,2-4,7-10H2,1H3,(H,20,21,23)
PubChem CID	10946905
ChEMBL	CHEMBL420475
IUPHAR	N/A
BindingDB	50130433
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
41463	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
41462	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
41464	5-hydroxytryptamine receptor 1D	P28221	HTR1D	Homo sapiens (Human)	377
41461	5-hydroxytryptamine receptor 1F	P30939	HTR1F	Homo sapiens (Human)	366

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