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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	dicyclomine
Molecular formula	C19H35NO2
IUPAC name	2-(diethylamino)ethyl 1-cyclohexylcyclohexane-1-carboxylate
Molecular weight	309.494
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	5.5
Synonyms	(1,1'-Bicyclohexyl)-1-carboxylic acid, 2-(diethylamino)ethyl ester Diethylaminocarbethoxybicyclohexyl hydrochloride 104959-55-9 DTXSID1022926 4KV4X8IF6V HSDB 3058 AC1L1F1K KBio3_001395 Bentyl (TN) LS-177325 Tox21_113571_1 BPBio1_000193 NCGC00015368-03 [Bicyclohexyl]-1-carboxylic acid, 2-(diethylamino)ethyl ester C19H35NO2 NCGC00024386-03 CURUTKGFNZGFSE-UHFFFAOYSA-N Prestwick2_000048 Dibent (TN) SPBio_002096 Dicycloverine Dicycloverine [INN:BAN] (Bicyclohexyl)-1-carboxylic acid, hydrochloride Diocyl hydrochloride 2-(diethylamino)ethyl 1-cyclohexylcyclohexanecarboxylate Formulex 77-19-0 J.L. 998 AKOS022107181 Kolantyl hydrochloride Spectrum5_000873 Bentylol (TN) MCULE-9110194493 Wyovin BSPBio_000175 NCGC00015368-06 CCG-204524 NSC-404381 D07XJM Sawamin Dicymine .beta.-Diethylaminoethyl-1-cyclohexylhexahydrobenzoate hydrochloride DSSTox_GSID_22926 2-diethylaminoethyl 1-cyclohexylcyclohexanecarboxylate GU8471000 AB00053456_14 KBio2_003982 Bentomine Lopac-D-7909 STL356799 Bicyclohexyl-1-carbonsaeure-2'diethylaminoethylester NCGC00015368-01 [1, 2-(diethylamino)ethyl ester, hydrochloride Byclomine (TN) NCGC00015368-11 CHEMBL1123 Prestwick0_000048 Di-Spaz (TN) Spasmoban Dicycloverin (Bicyclohexyl)-1-carboxylic acid, 2-(diethylamino)ethyl ester Dilomine (TN) 2-(diethylamino)ethyl 1,1'-bi(cyclohexyl)-1-carboxylate Dyspas IDI1_000162 AC1Q2ZDW KBioGR_001057 Bentyl hydrochloride LS-56640 UNII-4KV4X8IF6V BRD-K68507560-003-05-5 NCGC00015368-04 [Bicyclohexyl]-1-carboxylic acid, 2-(diethylamino)ethyl ester hydrochloride CAS-67-92-5 NCGC00024386-04 Cyclohexanecarboxylic acid, 1-cyclohexyl-, 2-(diethylamino)ethyl ester Prestwick3_000048 Dicicloverina Spectrum2_000590 Dicycloverine (Dicyclomine) Dicycloverinum DivK1c_000162 2-diethylaminoethyl 1-cyclohexylcyclohexane-1-carboxylate Formulex (TN) 856995-49-8 KBio1_000162 Atumin L000680 Spectrum_000934 Bentylol hydrochloride Merbentyl Wyovin hydrochloride BSPBio_002175 NCGC00015368-07 CHEBI:4514 NSC404381 SBI-0050417.P004 Dicyclomine Hcl Dicymine (TN) 1-Cyclohexylcyclohexanecarboxylic acid 2-(diethylamino)ethyl ester DSSTox_RID_76790 HMS3604H12 AB00053456_15 KBio2_006550 Bentyl Lopac0_000432 Tox21_113571 Bicyclohexyl-1-carboxylic acid 2-diethylamino-ethyl ester NCGC00015368-02 [1,1'-Bicyclohexyl]-1-carboxylic acid, 2-(diethylamino)ethyl ester C06951 NCGC00016300-01 CURUTKGFNZGFSE-UHFFFAOYSA- Prestwick1_000048 Di-syntramine SPBio_000440 Dicycloverin hydrochloride Dicycloverine (INN) (BICYCLOHEXYL)-1-CARBOXYLIC ACID, 2-(DIETHYLAMINO)ETHYL ESTER, HYDROCHLORIDE Diocyl 2-(diethylamino)ethyl 1-cyclohexylcyclohexane-1-carboxylate EINECS 201-009-4 67-92-5 (hydrochloride) InChI=1/C19H35NO2/c1-3-20(4-2)15-16-22-18(21)19(13-9-6-10-14-19)17-11-7-5-8-12-17/h17H,3-16H2,1-2H3 AC1Q2ZDX KBioSS_001414 Spectrum4_000509 Bentylol Mamiesan WLN: L6TJ A- AL6TJ AVO2N2&2 &GH BRD-K68507560-003-15-4 NCGC00015368-05 CAS-77-19-0 NINDS_000162 D07820 Procyclomin Dicicloverina [INN-Spanish] Spectrum3_000388 Dicycloverinum [INN-Latin] .beta.-Diethylaminoethyl 1-cyclohexylcyclohexanecarboxylate hydrochloride DSSTox_CID_2926 2-diethylaminoethyl 1-cyclohexylcyclohexane-1-carboxylate hydrochloride GTPL355 AB00053456 KBio2_001414 BDBM50010101 Lomine (TN) ST45026134 beta-Diethylaminoethyl 1-cyclohexylcyclohexanecarboxylate hydrochloride Merbentyl (TN) ZINC1530613 Byclomine NCGC00015368-08 Oxityl-P DB00804 SCHEMBL3317 Dicyclomine [INN] [ Show all ]
Inchi Key	CURUTKGFNZGFSE-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H35NO2/c1-3-20(4-2)15-16-22-18(21)19(13-9-6-10-14-19)17-11-7-5-8-12-17/h17H,3-16H2,1-2H3
PubChem CID	3042
ChEMBL	CHEMBL1123
IUPHAR	355
BindingDB	50010101
DrugBank	DB00804
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
51052	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
51053	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
51060	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
51061	5-hydroxytryptamine receptor 6	P50406	HTR6	Homo sapiens (Human)	440
51065	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
51051	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
51055	Histamine H2 receptor	P25021	HRH2	Homo sapiens (Human)	359
51059	Muscarinic acetylcholine receptor M1	P11229	CHRM1	Homo sapiens (Human)	460
51063	Muscarinic acetylcholine receptor M1	P08482	Chrm1	Rattus norvegicus (Rat)	460
51057	Muscarinic acetylcholine receptor M2	P08172	CHRM2	Homo sapiens (Human)	466
51058	Muscarinic acetylcholine receptor M2	P10980	Chrm2	Rattus norvegicus (Rat)	466
51062	Muscarinic acetylcholine receptor M3	P20309	CHRM3	Homo sapiens (Human)	590
51066	Muscarinic acetylcholine receptor M3	P08483	Chrm3	Rattus norvegicus (Rat)	589
51054	Muscarinic acetylcholine receptor M4	P08173	CHRM4	Homo sapiens (Human)	479
51056	Muscarinic acetylcholine receptor M4	P17200	CHRM4	Gallus gallus (Chicken)	490
51064	Muscarinic acetylcholine receptor M5	P08912	CHRM5	Homo sapiens (Human)	532
51067	Thyrotropin receptor	P16473	TSHR	Homo sapiens (Human)	764

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