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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2037520
Molecular formula	C24H25ClN4O2S
IUPAC name	3-[1-[5-(1,3-benzothiazol-2-yl)-5-oxopentyl]piperidin-4-yl]-6-chloro-1H-benzimidazol-2-one
Molecular weight	469.0
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	4.8
Synonyms	BDBM50384961
Inchi Key	CWYDVWDIVIJIOS-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H25ClN4O2S/c25-16-8-9-20-19(15-16)27-24(31)29(20)17-10-13-28(14-11-17)12-4-3-6-21(30)23-26-18-5-1-2-7-22(18)32-23/h1-2,5,7-9,15,17H,3-4,6,10-14H2,(H,27,31)
PubChem CID	60167451
ChEMBL	CHEMBL2037520
IUPHAR	N/A
BindingDB	50384961
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
52550	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
52547	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
52546	5-hydroxytryptamine receptor 7	P34969	HTR7	Homo sapiens (Human)	479
52548	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
523066	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
52549	D(4) dopamine receptor	P30729	Drd4	Rattus norvegicus (Rat)	387
523065	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467

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