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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL297933
Molecular formula	C29H31NO5
IUPAC name	(4aS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-4'-methoxyspiro[1,2,4,5,7a,13-hexahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-6,2'-1,3-dihydroindene]-7-one
Molecular weight	473.569
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	3.7
Synonyms	7-(4''-Methoxy-2''-spiroindanyl)naltrexone BDBM50058154
Inchi Key	CYGKSTHZZXBEKA-ZYRCJVDNSA-N
Inchi ID	InChI=1S/C29H31NO5/c1-34-21-4-2-3-18-12-27(13-19(18)21)15-29(33)22-11-17-7-8-20(31)24-23(17)28(29,26(35-24)25(27)32)9-10-30(22)14-16-5-6-16/h2-4,7-8,16,22,26,31,33H,5-6,9-15H2,1H3/t22?,26?,27?,28?,29-/m1/s1
PubChem CID	44292892
ChEMBL	CHEMBL297933
IUPHAR	N/A
BindingDB	50058154
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
53471	Delta-type opioid receptor	P32300	Oprd1	Mus musculus (Mouse)	372
53473	Kappa-type opioid receptor	P33534	Oprk1	Mus musculus (Mouse)	380
53474	Kappa-type opioid receptor	P41144	OPRK1	Cavia porcellus (Guinea pig)	380
53472	Mu-type opioid receptor	P97266	OPRM1	Cavia porcellus (Guinea pig)	98
53475	Mu-type opioid receptor	P42866	Oprm1	Mus musculus (Mouse)	398

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