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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL27251
Molecular formula	C18H18N2
IUPAC name	(6S,14R)-13-methyl-13-azapentacyclo[12.3.1.05,17.07,16.010,15]octadeca-1(17),2,4,7(16),8,10(15)-hexaen-6-amine
Molecular weight	262.356
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	1.6
Synonyms	(1S,5aR)-6-methyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]aceanthrylen-1-ylamine BDBM50087024 (1S)-6-Methyl-1,5,5aalpha,6,7,8-hexahydro-6-azabenzo[mno]aceanthrylene-1beta-amine 6-Methyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]aceanthrylen-1-ylamine
Inchi Key	DAKGDRVNCPHAPY-KDOFPFPSSA-N
Inchi ID	InChI=1S/C18H18N2/c1-20-8-7-10-5-6-13-17-15-11(9-14(20)16(10)17)3-2-4-12(15)18(13)19/h2-6,14,18H,7-9,19H2,1H3/t14-,18+/m1/s1
PubChem CID	10084076
ChEMBL	CHEMBL27251
IUPHAR	N/A
BindingDB	50087024
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
55101	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
55102	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
55107	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
55100	5-hydroxytryptamine receptor 7	P34969	HTR7	Homo sapiens (Human)	479
55106	5-hydroxytryptamine receptor 7	P32305	Htr7	Rattus norvegicus (Rat)	448
55103	Alpha-1A adrenergic receptor	P35348	ADRA1A	Homo sapiens (Human)	466
55099	Alpha-2A adrenergic receptor	P08913	ADRA2A	Homo sapiens (Human)	450
55104	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
55105	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443

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