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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL281048
Molecular formula	C18H18N2
IUPAC name	(6R,14R)-13-methyl-13-azapentacyclo[12.3.1.05,17.07,16.010,15]octadeca-1(17),2,4,7(16),8,10(15)-hexaen-6-amine
Molecular weight	262.356
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	1.6
Synonyms	(1R,5aR)-6-methyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]aceanthrylen-1-ylamine 6-Methyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]aceanthrylen-1-ylamine (6aR,12R)-4,5,6,6abeta-Tetrahydro-1,11-methano-12-amino-6-methyl-7H-dibenzo[de,g]quinoline BDBM50087035
Inchi Key	DAKGDRVNCPHAPY-RDTXWAMCSA-N
Inchi ID	InChI=1S/C18H18N2/c1-20-8-7-10-5-6-13-17-15-11(9-14(20)16(10)17)3-2-4-12(15)18(13)19/h2-6,14,18H,7-9,19H2,1H3/t14-,18-/m1/s1
PubChem CID	10706626
ChEMBL	CHEMBL281048
IUPHAR	N/A
BindingDB	50087035
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
55109	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
55113	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
55108	5-hydroxytryptamine receptor 7	P34969	HTR7	Homo sapiens (Human)	479
55111	5-hydroxytryptamine receptor 7	P32305	Htr7	Rattus norvegicus (Rat)	448
55110	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
55112	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444

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