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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000106452
Molecular formula	C17H24FN3O
IUPAC name	1-[4-[4-(2-fluorophenyl)piperazin-1-yl]piperidin-1-yl]ethanone
Molecular weight	305.397
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	2.0
Synonyms	1-[4-[4-(2-fluorophenyl)-1-piperazinyl]-1-piperidinyl]ethanone CHEMBL1721257 SR-01000208151-1 Cambridge id 5410004 SMR000103419 1-[4-[4-(2-fluorophenyl)piperazin-1-yl]piperidin-1-yl]ethanone cid_743199 SR-01000208151-3 AC1LEWVF MolPort-045-968-224 SR-01000208151 1-[4-[4-(2-fluorophenyl)piperazino]piperidino]ethanone HMS2441C20 BDBM38235 Oprea1_549991 [ Show all ]
Inchi Key	DGZHDCOAURPHLR-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H24FN3O/c1-14(22)19-8-6-15(7-9-19)20-10-12-21(13-11-20)17-5-3-2-4-16(17)18/h2-5,15H,6-13H2,1H3
PubChem CID	743199
ChEMBL	CHEMBL1721257
IUPHAR	N/A
BindingDB	38235
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
59752	5-hydroxytryptamine receptor 2A	P35363	Htr2a	Mus musculus (Mouse)	471
470297	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
59751	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400

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