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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	N-(2-[4-(4-Chlorophenyl)piperazin-1-yl]ethyl)-3-methoxybenzamide
Molecular formula	C20H24ClN3O2
IUPAC name	N-[2-[4-(4-chlorophenyl)piperazin-1-yl]ethyl]-3-methoxybenzamide
Molecular weight	373.881
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	3.4
Synonyms	NCGC00015262-04 SR-01000075777-1 AKOS024728383 F5264-0494 n-(2-(4-(4-chlorophenyl)piperazin-1-yl)ethyl)-3-methoxybenzamide NCGC00260972-01 CCG-204382 HMS3373J10 N-[2-[4-(4-chlorophenyl)piperazin-1-yl]ethyl]-3-methoxybenzamide NCGC00015262-02 SMR001230850 CTK8G1437 LP00287 NCGC00093740-01 Tox21_500287 BDBM50068366 HMS2230B03 N-{2-[4-(4-Chloro-phenyl)-piperazin-1-yl]-ethyl}-3-methoxy-benzamide PB-12 Lopac-C-7230 NCGC00015262-03 SR-01000075777 AC1MTLV6 EU-0100287 MLS002153518 NCGC00093740-02 C 7230 HMS3260J16 N-[2-(4-(4-Chlorophenyl)piperazin-1-yl)ethyl]-3-methoxybenzamide NCGC00015262-01 SCHEMBL1322020 CHEMBL93403 Lopac0_000287 [ Show all ]
Inchi Key	DQVARXSGNFBPMB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H24ClN3O2/c1-26-19-4-2-3-16(15-19)20(25)22-9-10-23-11-13-24(14-12-23)18-7-5-17(21)6-8-18/h2-8,15H,9-14H2,1H3,(H,22,25)
PubChem CID	3626837
ChEMBL	CHEMBL93403
IUPHAR	N/A
BindingDB	50068366
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
66657	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
66654	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
66658	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
66652	D(3) dopamine receptor	P19020	Drd3	Rattus norvegicus (Rat)	446
66655	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467
66656	D(4) dopamine receptor	P30729	Drd4	Rattus norvegicus (Rat)	387
66653	Muscarinic acetylcholine receptor M1	P08482	Chrm1	Rattus norvegicus (Rat)	460
471156	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593

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