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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL431266
Molecular formula	C22H35NO
IUPAC name	3-[(3R,4R)-1-(3-cyclohexylpropyl)-3,4-dimethylpiperidin-4-yl]phenol
Molecular weight	329.528
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	6.6
Synonyms	SCHEMBL12168480 3-[1-(3-Cyclohexyl-propyl)-3,4-dimethyl-piperidin-4-yl]-phenol ZINC13833042 3-[(3R,4R)-1-(3-Cyclohexylpropyl)-3,4-dimethyl-4-piperidinyl]phenol BDBM50045785
Inchi Key	DRIFNPBKGHUWAN-PGRDOPGGSA-N
Inchi ID	InChI=1S/C22H35NO/c1-18-17-23(14-7-10-19-8-4-3-5-9-19)15-13-22(18,2)20-11-6-12-21(24)16-20/h6,11-12,16,18-19,24H,3-5,7-10,13-15,17H2,1-2H3/t18-,22+/m0/s1
PubChem CID	10359237
ChEMBL	CHEMBL431266
IUPHAR	N/A
BindingDB	50045785
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
66994	Kappa-type opioid receptor	P33534	Oprk1	Mus musculus (Mouse)	380
66996	Kappa-type opioid receptor	P34975	Oprk1	Rattus norvegicus (Rat)	380
66997	Kappa-type opioid receptor	P41144	OPRK1	Cavia porcellus (Guinea pig)	380
66993	Mu-type opioid receptor	P33535	Oprm1	Rattus norvegicus (Rat)	398
66995	Mu-type opioid receptor	P42866	Oprm1	Mus musculus (Mouse)	398

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