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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2113386
Molecular formula	C20H22IN3O2S
IUPAC name	1-(2-iodophenyl)-N-[3-[[(2R)-pyrrolidin-2-yl]methyl]-1H-indol-5-yl]methanesulfonamide
Molecular weight	495.379
Hydrogen bond acceptor	4
Hydrogen bond donor	3
XlogP	3.5
Synonyms	N/A
Inchi Key	DXNOFPQQCQAJFH-MRXNPFEDSA-N
Inchi ID	InChI=1S/C20H22IN3O2S/c21-19-6-2-1-4-14(19)13-27(25,26)24-17-7-8-20-18(11-17)15(12-23-20)10-16-5-3-9-22-16/h1-2,4,6-8,11-12,16,22-24H,3,5,9-10,13H2/t16-/m1/s1
PubChem CID	71459954
ChEMBL	CHEMBL2113386
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
71448	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
71452	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
71451	5-hydroxytryptamine receptor 1D	P28221	HTR1D	Homo sapiens (Human)	377
71444	5-hydroxytryptamine receptor 1F	P30939	HTR1F	Homo sapiens (Human)	366
71447	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
71449	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
71446	5-hydroxytryptamine receptor 6	P50406	HTR6	Homo sapiens (Human)	440
71454	5-hydroxytryptamine receptor 7	P34969	HTR7	Homo sapiens (Human)	479
71445	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
71450	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
71453	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467

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