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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL384547
Molecular formula	C23H20F3N3O
IUPAC name	(E)-N-(4-amino-2-cyclobutylquinolin-6-yl)-3-[4-(trifluoromethyl)phenyl]prop-2-enamide
Molecular weight	411.428
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	4.8
Synonyms	SCHEMBL6204528 BDBM50193620 SCHEMBL6204521 (E)-N-(4-amino-2-cyclobutylquinolin-6-yl)-3-(4-(trifluoromethyl)phenyl)acrylamide
Inchi Key	DZBRSGDTRPYNOH-IZZDOVSWSA-N
Inchi ID	InChI=1S/C23H20F3N3O/c24-23(25,26)16-7-4-14(5-8-16)6-11-22(30)28-17-9-10-20-18(12-17)19(27)13-21(29-20)15-2-1-3-15/h4-13,15H,1-3H2,(H2,27,29)(H,28,30)/b11-6+
PubChem CID	44417947
ChEMBL	CHEMBL384547
IUPHAR	N/A
BindingDB	50193620
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
72488	Melanin-concentrating hormone receptor 1	Q99705	MCHR1	Homo sapiens (Human)	422
72489	Melanin-concentrating hormone receptor 2	Q969V1	MCHR2	Homo sapiens (Human)	340

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