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Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
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Ligand

Name	ondansetron
Molecular formula	C18H19N3O
IUPAC name	9-methyl-3-[(2-methylimidazol-1-yl)methyl]-2,3-dihydro-1H-carbazol-4-one
Molecular weight	293.37
Hydrogen bond acceptor	2
Hydrogen bond donor	0
XlogP	2.3
Synonyms	DSSTox_CID_3393 GR-38032 1,2,3,9-Tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1yl)methyl]-4H-carbazol-4-one HMS3371E18 4H-Carbazol-4-one, 1,2,3,9-tetrahydro-9-methyl-3-((2-methyl-1H-imidazol-1-yl)methyl)- KS-5227 9-methyl-3-[(2-methylimidazol-1-yl)methyl]-2,3-dihydro-1H-carbazol-4-one NCGC00179341-02 AB00373674-17 Ondansetron (base and/or unspecified salts) AKOS000599484 Oprea1_435466 BCP9001025 QC-660 C07325 SCHEMBL4542 CPD001307702 STK370548 Z1741971217 Zuplenz Tox21_113048 DTXSID8023393 1,2,3,4-Tetrahydro-9-methyl-3-(2-methyl-1H-imidazol-1-ylmethyl)carbazol-4-one GR38032 103639-04-9 I06-0687 9-methyl-3-((2-methyl-1H-imidazol-1-yl)methyl)-1,2,3,9-tetrahydro-4H-carbazol-4-one LS-51878 99614-01-4 (mono-hydrochloride) NCI60_022780 AB2000413 ONDANSETRON HCl Apo-ondansetron PMS-ondansetron BR-29654 s1996 CAS_68647 SPBio_002938 D00456 ZOFRAN IN PLASTIC CONTAINER DB00904 GR 38032 1,2,3,9-tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-4H- carbazol-4-one HMS2090H16 116002-70-1 KB-308401 9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-1,2,3,9-tetrahydro-4H-carbazol-4-one MolPort-001-944-253 AB00373674 Odansetron [common misspelling of ondansetron] ACN-049703 Ondansetron [USP:INN:BAN] BC220610 Prestwick2_001058 BRN 3622981 SBB066158 ST077669 Zophren TimTec1_001750 DSSTox_GSID_23393 GR-38032F 1,2,3,9-tetrahydro-9-methyl-3-[(2-methyl-1H-imidazole-1 -yl)methyl]-4H-carbazol-4-one HSDB 8304 L000456 9-methyl-3-[(2-methylimidazolyl)methyl]-1,2,3,9-tetrahydro-4aH-carbazol-4-one NCGC00179341-04 AB00373674_18 Ondansetron (JAN/USP/INN) AKOS016340526 Oprea1_852372 BDBM85330 Ratio-ondansetron C18H19N3O SMR001307702 CS-2393 Zofran Tox21_113048_1 FELGMEQIXOGIFQ-UHFFFAOYSA-N 1,2,3,9,-Tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-4H-carbazol-4-one GR38032F 103639-04-9 (mono-hydrochloride dihydrate) I06-1329 9-Methyl-3-((2-methyl-1H-imidazol-1-yl)methyl)-2,3-dihydro-1H-carbazol-4(9H)-one MCULE-9438746800 99614-02-5 Novo-ondansetron AC-28927 Ondansetron Injection BAS 00717177 Prestwick0_001058 BRD-A19736161-001-01-8 SAM002589958 CBDivE_008994 SR-01000763250 D0K7WK Zofran ODT DESMETHYLONDANSETRON GR 38032X 1,2,3,9-tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-4H-carbazol-4-one HMS3259H08 39O049 KS-00000JSZ 9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-2,3,4,9-tetrahydro-1H-carbazol-4-one NC00706 AB00373674-15 ACT02589 Ondansetron, (+,-)-Isomer BCP28911 Prestwick3_001058 BSPBio_001016 SC-07554 CHEMBL46 ST2412612 VA11441 Zudan TL8006071 DSSTox_RID_77011 (RS)-1,2,3,9-Tetrahydro-9-methyl-3-(2-methylimidazol-1-ylmethyl)carbazol-4-one GR-38032F/GR-38032 1,2,3,9-tetrahydro-9-methyl-3-[(2-methyl-1H-imidazole-1-yl)methyl]-4H-carbazol-4-one HY-B0002B 9-Methyl-3- (2-methyl-imidazol-1ylmethyl)-1,2,3,9-tetrahydro-carbazol-4-one LS-172305 99614-01-4 NCGC00179341-07 AB00373674_19 ondansetron (Zofran) AN-6592 PHL-ondansetron BPBio1_001118 S-2116 CAS-99614-02-5 SN-307 CTK8G2184 Zofran (TN) FT-0631004 1,2,3,9-Tetrahydro-9-methyl-3-((2-methyl-1H-imidazol-1-yl)methyl)-4H-carbazol-4-one GTPL2290 108303-49-7 I544 9-Methyl-3-(2-methyl-imidazol-1-ylmethyl)-1,2,3,9-tetrahydro-carbazol-4-one MLS006011928 AB0013753 NSC_68647 AC1L1IIM Ondansetron [USAN:INN:BAN] BBL010304 Prestwick1_001058 BRD-A19736161-003-03-0 Sandoz ondansetron CHEBI:7773 SR-01000763250-4 Zofran ODT (TN) [ Show all ]
Inchi Key	FELGMEQIXOGIFQ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H19N3O/c1-12-19-9-10-21(12)11-13-7-8-16-17(18(13)22)14-5-3-4-6-15(14)20(16)2/h3-6,9-10,13H,7-8,11H2,1-2H3
PubChem CID	4595
ChEMBL	CHEMBL46
IUPHAR	N/A
BindingDB	85330
DrugBank	DB00904
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
76362	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
76373	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
76348	5-hydroxytryptamine receptor 1B	P28564	Htr1b	Rattus norvegicus (Rat)	386
76375	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
76363	5-hydroxytryptamine receptor 1D	P28565	Htr1d	Rattus norvegicus (Rat)	374
76349	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
76364	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
76355	5-hydroxytryptamine receptor 2C	P08909	Htr2c	Rattus norvegicus (Rat)	460
76359	5-hydroxytryptamine receptor 4	O70528	HTR4	Cavia porcellus (Guinea pig)	388
76361	5-hydroxytryptamine receptor 4	Q62758	Htr4	Rattus norvegicus (Rat)	406
76370	5-hydroxytryptamine receptor 4	Q13639	HTR4	Homo sapiens (Human)	388
76365	5-hydroxytryptamine receptor 5B	P35365	Htr5b	Rattus norvegicus (Rat)	370
555764	5-hydroxytryptamine receptor 7	P32305	Htr7	Rattus norvegicus (Rat)	448
76350	Alpha-2A adrenergic receptor	P22909	Adra2a	Rattus norvegicus (Rat)	450
76371	Cholecystokinin receptor type A	P30551	Cckar	Rattus norvegicus (Rat)	444
76353	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
76367	D(1A) dopamine receptor	P18901	Drd1	Rattus norvegicus (Rat)	446
76354	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
555765	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
76372	D(3) dopamine receptor	P19020	Drd3	Rattus norvegicus (Rat)	446