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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL197245
Molecular formula	C21H21Cl2N3O3
IUPAC name	2-(2,4-dichlorophenoxy)-N-[2-[2-hydroxyethyl(methyl)amino]-4-methylquinolin-6-yl]acetamide
Molecular weight	434.317
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	4.5
Synonyms	BDBM50172415 2-(2,4-Dichloro-phenoxy)-N-{2-[(2-hydroxy-ethyl)-methyl-amino]-4-methyl-quinolin-6-yl}-acetamide
Inchi Key	FKLOHGYBYOWNQD-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H21Cl2N3O3/c1-13-9-20(26(2)7-8-27)25-18-5-4-15(11-16(13)18)24-21(28)12-29-19-6-3-14(22)10-17(19)23/h3-6,9-11,27H,7-8,12H2,1-2H3,(H,24,28)
PubChem CID	11495754
ChEMBL	CHEMBL197245
IUPHAR	N/A
BindingDB	50172415
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
80597	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
80598	Melanin-concentrating hormone receptor 1	Q99705	MCHR1	Homo sapiens (Human)	422
80599	Melanin-concentrating hormone receptor 2	Q969V1	MCHR2	Homo sapiens (Human)	340

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