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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL318571
Molecular formula	C18H28N4O2S
IUPAC name	2-[5-[(1,1-dioxo-5-propan-2-yl-1,2,5-thiadiazolidin-2-yl)methyl]-1H-indol-3-yl]-N,N-dimethylethanamine
Molecular weight	364.508
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	1.9
Synonyms	SCHEMBL8807319 2-[[3-[2-(Dimethylamino)ethyl]-1H-indol-5-yl]methyl]-5-isopropyl-1,2,5-thiadiazolidine 1,1-dioxide BDBM50422023
Inchi Key	HEFIDNYHXDTDFP-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H28N4O2S/c1-14(2)22-10-9-21(25(22,23)24)13-15-5-6-18-17(11-15)16(12-19-18)7-8-20(3)4/h5-6,11-12,14,19H,7-10,13H2,1-4H3
PubChem CID	9998879
ChEMBL	CHEMBL318571
IUPHAR	N/A
BindingDB	50422023
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
112673	5-hydroxytryptamine receptor 1D	P79400	HTR1D	Sus scrofa (Pig)	291
112675	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
112674	5-hydroxytryptamine receptor 5A	P47898	HTR5A	Homo sapiens (Human)	357

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