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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL177238
Molecular formula	C20H19ClFN3O2
IUPAC name	2-chloro-4-fluoro-N-[3-(1-methylpiperidin-4-yl)furo[3,2-b]pyridin-5-yl]benzamide
Molecular weight	387.839
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	3.8
Synonyms	BDBM50137538 N-[3-(1-Methyl-4-piperidinyl)furo[3,2-b]pyridine-5-yl]-2-chloro-4-fluorobenzamide 2-Chloro-4-fluoro-N-[3-(1-methyl-piperidin-4-yl)-furo[3,2-b]pyridin-5-yl]-benzamide
Inchi Key	IWNPMSHFWIZUSM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H19ClFN3O2/c1-25-8-6-12(7-9-25)15-11-27-17-4-5-18(23-19(15)17)24-20(26)14-3-2-13(22)10-16(14)21/h2-5,10-12H,6-9H2,1H3,(H,23,24,26)
PubChem CID	44387174
ChEMBL	CHEMBL177238
IUPHAR	N/A
BindingDB	50137538
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
143459	5-hydroxytryptamine receptor 1F	P30939	HTR1F	Homo sapiens (Human)	366

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