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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SMR000047376
Molecular formula	C19H21ClN8
IUPAC name	2-N-(4-chlorophenyl)-6-[(4-pyridin-2-ylpiperazin-1-yl)methyl]-1,3,5-triazine-2,4-diamine
Molecular weight	396.883
Hydrogen bond acceptor	8
Hydrogen bond donor	2
XlogP	2.9
Synonyms	AKOS005512111 MLS002584691 STK203210 2-N-(4-chlorophenyl)-6-[(4-pyridin-2-ylpiperazin-1-yl)methyl]-1,3,5-triazine-2,4-diamine CHEMBL1600031 N-(4-chlorophenyl)-6-{[4-(pyridin-2-yl)piperazin-1-yl]methyl}-1,3,5-triazine-2,4-diamine [4-amino-6-[[4-(2-pyridyl)piperazino]methyl]-s-triazin-2-yl]-(4-chlorophenyl)amine AC1LDF7E MCULE-2019357256 BDBM48928 MolPort-000-488-964 STK589571 cid_666078 N2-(4-chlorophenyl)-6-[(4-pyridin-2-ylpiperazin-1-yl)methyl]-1,3,5-triazine-2,4-diamine {4-amino-6-[(4-(2-pyridyl)piperazinyl)methyl](1,3,5-triazin-2-yl)}(4-chlorophe nyl)amine AKOS002211204 MLS000084243 ST50133329 (4E)-4-[(4-chlorophenyl)imino]-6-{[4-(pyridin-2-yl)piperazin-1-yl]methyl}-4,5-dihydro-1,3,5-triazin-2-amine MolPort-000-806-157 ZINC95483251 827002-46-0 HMS2360A24 N2-(4-chlorophenyl)-6-[[4-(2-pyridinyl)-1-piperazinyl]methyl]-1,3,5-triazine-2,4-diamine [ Show all ]
Inchi Key	JBQYOMAORVUETK-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H21ClN8/c20-14-4-6-15(7-5-14)23-19-25-16(24-18(21)26-19)13-27-9-11-28(12-10-27)17-3-1-2-8-22-17/h1-8H,9-13H2,(H3,21,23,24,25,26)
PubChem CID	666078
ChEMBL	CHEMBL1600031
IUPHAR	N/A
BindingDB	48928
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
146963	5-hydroxytryptamine receptor 2A	P35363	Htr2a	Mus musculus (Mouse)	471
146962	D(1B) dopamine receptor	P21918	DRD5	Homo sapiens (Human)	477
146961	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
146960	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400

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