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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	DUP-734 free base
Molecular formula	C17H22FNO
IUPAC name	2-[1-(cyclopropylmethyl)piperidin-4-yl]-1-(4-fluorophenyl)ethanone
Molecular weight	275.367
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	3.2
Synonyms	KWRMWQDKOGFMKP-UHFFFAOYSA-N 1-(4-Fluorophenyl)-2-[1-(cyclopropylmethyl)piperidin-4-yl]ethanone AC1L3TQY SCHEMBL7358803 1-(Cyclopropylmethyl)-4-[2-(4-fluorophenyl)-2-oxoethyl]piperidine hydrobromide CHEMBL42228 DTXSID80159262 ZINC4902 2-[1-(cyclopropylmethyl)piperidin-4-yl]-1-(4-fluorophenyl)ethanone L004958 1-(Cyclopropylmethyl)-4-(2'-(4"-fluorophenyl)-2'-oxoethyl)piperidine BDBM50002218 CHEMBL543412 T033730RWW 135135-80-7 LS-187606 1-(cyclopropylmethyl)-4-(2'-(4''-fluorophenyl)-2'-oxo-ethyl)-piperidine D0Z4QV UNII-T033730RWW 2-(1-Cyclopropylmethyl-piperidin-4-yl)-1-(4-fluoro-phenyl)-ethanone; hydrobromide [ Show all ]
Inchi Key	KWRMWQDKOGFMKP-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H22FNO/c18-16-5-3-15(4-6-16)17(20)11-13-7-9-19(10-8-13)12-14-1-2-14/h3-6,13-14H,1-2,7-12H2
PubChem CID	121968
ChEMBL	CHEMBL42228
IUPHAR	N/A
BindingDB	50002218
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
180090	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
180088	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
180085	D(1A) dopamine receptor	Q61616	Drd1	Mus musculus (Mouse)	446
180086	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
180087	D(2) dopamine receptor	P20288	DRD2	Bos taurus (Bovine)	444
180089	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
460815	D(2) dopamine receptor	P61168	Drd2	Mus musculus (Mouse)	444

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