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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3262393
Molecular formula	C24H25N3O
IUPAC name	3-[2-(4-naphthalen-1-ylpiperazin-1-yl)ethyl]-1H-indol-5-ol
Molecular weight	371.484
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	4.8
Synonyms	BDBM50015220
Inchi Key	LGZBUKYZDPMWQV-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H25N3O/c28-20-8-9-23-22(16-20)19(17-25-23)10-11-26-12-14-27(15-13-26)24-7-3-5-18-4-1-2-6-21(18)24/h1-9,16-17,25,28H,10-15H2
PubChem CID	90656711
ChEMBL	CHEMBL3262393
IUPHAR	N/A
BindingDB	50015220
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
187214	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
187210	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
187213	5-hydroxytryptamine receptor 1D	P28565	Htr1d	Rattus norvegicus (Rat)	374
187205	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
187212	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
187207	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
187206	5-hydroxytryptamine receptor 4	Q13639	HTR4	Homo sapiens (Human)	388
187208	5-hydroxytryptamine receptor 5A	P47898	HTR5A	Homo sapiens (Human)	357
187211	5-hydroxytryptamine receptor 6	P50406	HTR6	Homo sapiens (Human)	440
187209	5-hydroxytryptamine receptor 7	P34969	HTR7	Homo sapiens (Human)	479

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