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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MK-4256
Molecular formula	C27H23FN8O
IUPAC name	3-[(1R,3R)-3-[5-(4-fluorophenyl)-1H-imidazol-2-yl]-1-(1-methylpyrazol-4-yl)-2,3,4,9-tetrahydropyrido[3,4-b]indol-1-yl]-5-methyl-1,2,4-oxadiazole
Molecular weight	494.534
Hydrogen bond acceptor	7
Hydrogen bond donor	3
XlogP	3.1
Synonyms	BDBM50400517 MK4256 CS-7919 3-[(1R,3R)-3-[5-(4-fluorophenyl)-1H-imidazol-2-yl]-1-(1-methylpyrazol-4-yl)-2,3,4,9-tetrahydropyrido[3,4-b]indol-1-yl]-5-methyl-1,2,4-oxadiazole MK 4256 GTPL10114 CHEMBL2204935 HY-13466 [ Show all ]
Inchi Key	NTIFDLOQPKMIJK-AJTFRIOCSA-N
Inchi ID	InChI=1S/C27H23FN8O/c1-15-31-26(35-37-15)27(17-12-30-36(2)14-17)24-20(19-5-3-4-6-21(19)32-24)11-22(34-27)25-29-13-23(33-25)16-7-9-18(28)10-8-16/h3-10,12-14,22,32,34H,11H2,1-2H3,(H,29,33)/t22-,27-/m1/s1
PubChem CID	56927659
ChEMBL	CHEMBL2204935
IUPHAR	N/A
BindingDB	50400517
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
231522	Somatostatin receptor type 1	P30872	SSTR1	Homo sapiens (Human)	391
231527	Somatostatin receptor type 2	P30874	SSTR2	Homo sapiens (Human)	369
231524	Somatostatin receptor type 3	P30935	Sstr3	Mus musculus (Mouse)	428
231526	Somatostatin receptor type 3	P32745	SSTR3	Homo sapiens (Human)	418
231525	Somatostatin receptor type 4	P31391	SSTR4	Homo sapiens (Human)	388
231523	Somatostatin receptor type 5	P35346	SSTR5	Homo sapiens (Human)	364

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