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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Sch 58261
Molecular formula	C18H15N7O
IUPAC name	4-(furan-2-yl)-10-(2-phenylethyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(9),2,4,7,11-pentaen-7-amine
Molecular weight	345.366
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	2.4
Synonyms	BRD-K81225797-001-01-5 D07ESH GTPL431 LP01259 PDSP2_001183 SCHEMBL537287 [3H]-SCH 58261 2-(2-Furanyl)-7-(2-phenylethyl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine 5-Amino-7-(2-phenylethyl)-2-(2-furyl)-pyrazolo(4,3-e)-1,2,4-triazolo(1,5-c)pyrimidine AKOS022181216 AS-16830 CHEBI:93424 DB-043446 HY-19533 MolPort-003-983-679 s8104 Tox21_501259 2-Furan-2-yl-7-phenethyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamine(SCH 58261) 7-(2-phenylethyl)-5-amino-2-(2-furyl)-pyrazolo-[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine BDBM50048466 CS-5639 FT-0643554 KS-00000H1R NCGC00261944-01 Sch-58261 ZB000632 160098-96-4 4309023MAH AJ-08272 AN-17000 C-35635 D0J8LD HMS3263L20 LS-184256 PF-1913539 SP-341 [3H]SCH 58261 2-(Furan-2-yl)-7-phenethyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine 5-amino-7-(phenylethyl)-2-(2-furyl)-pyrazolo-[4,3-e]-1,2,4-triazolo-[1,5-c]-pyrimidine B6995 DTXSID80166799 J-009674 NCGC00092350-01 UNII-4309023MAH 4-(furan-2-yl)-10-(2-phenylethyl)-3,5,6,8,10,11-hexaazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2,4,7,11-pentaen-7-amine 7H-Pyrazolo(4,3-e)(1,2,4)triazolo(1,5-c)pyrimidin-5-amine, 2-(2-furanyl)-7-(2-phenylethyl)- BN0475 CTK8E9527 GTPL403 L000548 PDSP1_001199 Sch58261 ZINC6170 2-(2-Furanyl)-7-(2-phenylethyl)-7H-pyrazolo[4,3-e][1,2,4]triazolo [1,5-c]pyrimidin-5-amine AK-60772 AOB5053 CCG-222563 D0S6KU HMS3268F20 MFCD00933778 RT-015677 ST24039655 2-Furan-2-yl-7-phenethyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamine BCP14638 CHEMBL17127 EX-A1464 KB-275290 NCGC00092350-02 SCH 58261, >=98% (HPLC), solid UTLPKQYUXOEJIL-UHFFFAOYSA-N AC1L423J [ Show all ]
Inchi Key	UTLPKQYUXOEJIL-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H15N7O/c19-18-22-16-13(11-20-24(16)9-8-12-5-2-1-3-6-12)17-21-15(23-25(17)18)14-7-4-10-26-14/h1-7,10-11H,8-9H2,(H2,19,22)
PubChem CID	176408
ChEMBL	CHEMBL17127
IUPHAR	431, 403
BindingDB	50048466
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
345178	Adenosine receptor A1	P30542	ADORA1	Homo sapiens (Human)	326
345180	Adenosine receptor A1	P28190	ADORA1	Bos taurus (Bovine)	326
345181	Adenosine receptor A1	P25099	Adora1	Rattus norvegicus (Rat)	326
345175	Adenosine receptor A2a	P29274	ADORA2A	Homo sapiens (Human)	412
345176	Adenosine receptor A2a	P30543	Adora2a	Rattus norvegicus (Rat)	410
345179	Adenosine receptor A2b	P29275	ADORA2B	Homo sapiens (Human)	332
345183	Adenosine receptor A2b	P29276	Adora2b	Rattus norvegicus (Rat)	332
345177	Adenosine receptor A3	P0DMS8	ADORA3	Homo sapiens (Human)	318
345182	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446

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