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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3936595
Molecular formula	C20H23N3O3
IUPAC name	1-(2,3-dihydroindol-1-yl)-2-[(2S)-2-(pyridin-3-yloxymethyl)morpholin-4-yl]ethanone
Molecular weight	353.422
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	1.7
Synonyms	US9079895, 20s US9079895, 21s BDBM186930 SCHEMBL14062013
Inchi Key	XYHRHHHLNLGIRG-SFHVURJKSA-N
Inchi ID	InChI=1S/C20H23N3O3/c24-20(23-9-7-16-4-1-2-6-19(16)23)14-22-10-11-25-18(13-22)15-26-17-5-3-8-21-12-17/h1-6,8,12,18H,7,9-11,13-15H2/t18-/m0/s1
PubChem CID	71062889
ChEMBL	CHEMBL3936595
IUPHAR	N/A
BindingDB	186930
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
546857	5-hydroxytryptamine receptor 1A	Q64264	Htr1a	Mus musculus (Mouse)	421
546851	5-hydroxytryptamine receptor 2A	P35363	Htr2a	Mus musculus (Mouse)	471
546852	5-hydroxytryptamine receptor 2B	Q02152	Htr2b	Mus musculus (Mouse)	479
546853	D(1A) dopamine receptor	Q61616	Drd1	Mus musculus (Mouse)	446
546854	D(1B) dopamine receptor	Q8BLD9	Drd5	Mus musculus (Mouse)	478
546858	D(2) dopamine receptor	P61168	Drd2	Mus musculus (Mouse)	444
546855	D(3) dopamine receptor	P30728	Drd3	Mus musculus (Mouse)	446
546856	D(4) dopamine receptor	P51436	Drd4	Mus musculus (Mouse)	387

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