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Structure of PDB 6uo1 Chain 2r Binding Site BS01

Receptor Information >6uo1 Chain 2r (length=68) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure] AKVKATLGEFDLRDYRNVEVLKRFLSETGKILPRRRTGLSAKEQRILAKT IKRARILGLLPFTEKLVR

Ligand information >6uo1 Chain 2a (length=1503) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure] uuggagaguuugauccuggcucagggugaacgcuggcggcgugccuaaga caugcaagucgugcgggccgcgggguacuccguggucagcggcggacggg ugaguaacgcgugggugaccuacccggaagagggggacaacccggggaaa cucgggcuaaucccccauguggacccgccccuugggguguguccaaaggg cuuugcccgcuuccggaugggcccgcgucccaucagcuaguugguggggu aauggcccaccaaggcgacgacggguagccggucugagaggauggccggc cacaggggcacugagacacgggccccacuccuacgggaggcagcaguuag gaaucuuccgcaaugggcgcaagccugacggagcgacgccgcuuggagga agaagcccuucgggguguaaacuccugaacccgggacgaaacccccgacg aggggacugacgguaccgggguaauagcgccggccaacuccgugccagca gccgcgguaauacggagggcgcgagcguuacccggauucacugggcguaa agggcguguaggcggccuggggcgucccaugugaaagaccacggcucaac cgugggggagcgugggauacgcucaggcuagacggugggagaggguggug gaauucccggaguagcggugaaaugcgcagauaccgggaggaacgccgau ggcgaaggcagccaccugguccacccgugacgcugaggcgcgaaagcgug gggagcaaaccggauuagauacccggguaguccacgcccuaaacgaugcg cgcuaggucucugggucuccugggggccgaagcuaacgcguuaagcgcgc cgccuggggaguacggccgcaaggcugaaacucaaaggaauugacggggg cccgcacaagcgguggagcaugugguuuaauucgaagcaacgcgaagaac cuuaccaggccuugacaugcuagggaacccgggugaaagccuggggugcc ccgcgaggggagcccuagcacaggugcugcauggccgucgucagcucgug ccgugagguguuggguuaagucccgcaacgagcgcaacccccgccguuag uugccagcgguucggccgggcacucuaacgggacugcccgcgaaagcggg aggaaggaggggacgacgucuggucagcauggcccuuacggccugggcga cacacgugcuacaaugcccacuacaaagcgaugccacccggcaacgggga gcuaaucgcaaaaaggugggcccaguucggauuggggucugcaacccgac cccaugaagccggaaucgcuaguaaucgcggaucagccaugccgcgguga auacguucccgggccuuguacacaccgcccgucacgccaugggagcgggc ucuacccgaagucgccgggagccuacgggcaggcgccgaggguagggccc gugacuggggcgaagucguaacaagguagcuguaccggaaggugcggcug gau .....<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<..<..<< <.<<<..<<<..<<.<<<<<<<<<....>>>>>>>>>.>>>>>......< <.......<<<<<<<<..<<...<<<<<<<.<<<<<....<<<<<..... .>>>>>.....>>>>>...<<<<<.<<<<<....>>>>>.>>>>>..<<< <...>>>>.>>>>>>>..>>>>>>>>>><<<....<<<..<<<<<<<<.. .....>>>>>>>>>>>......>>>..<<<<<<<<....>>>>...>>>> .>>.<<<<<.<.........>>>>>>.<<<<....>>>>...>>>>>>>. .......<<<....<<<<....>>>>..>>>..>>.>>>>>>..<<<<.. ....<<<<....>>>>.....>>>>....<<<<<........<<<<.... .>>>>..........>>>>>......<<<<<(((...<<<<<.....<<. )))>>.......>>>>>>>>>>..>>>>>>>>>..........<<<((.. ...<<<<...<<<.<<<<<<.<<<<<<<<<<<......<<<<<<.....> >>>>>....>>>>>>>..>>>>>>>>>>...<<<<<<<<...<<<<<<<. ...<<<<<<<.<..<<<......>>>.....>.>>>>>>>.......... .<<....>>.>>>>>>>..>>>>>.>>>...>>>...>>>>....<<<<< <...<<...<<<<.........>>>>...>>>>>>>>..........<<< <<<..<<<<<<<<<<...>>>>>>>>>>...<<..))>>.....>>>>>> .>>>.<<<......<<<<....>>>>....>>>..)))).]<<<<<.<<< <<<<.<<.<<<<<<..<<<<<<<<<<......<<........>>...... ....<<<<<<<......<<<<<<<...<<<<<<<....>>>>>>>....< <......>>....>>>>>>>.<<<.<<<..<<<<<<.......<<<<<<< <<....>>>..<<<<......>>>>..>>>>>>.....<<<<.<<<<<<< ..<<<..<<<.....>>>>>>...>>>>>>>.....<<<<<....>>>>> ........>>>>.........>>>...>>>>>>>>>...>>>>>>>...> >.>>>>>>>>.....<<<<<<<.....<<<..<<..<<<<....>>>>.. >>....>>>.....>>>>>>>......<....<<<<<<<........>>> >>>>....>.....>>>>>>....<<<<<<<..........>>>>>>>.. ....>>...>>>>>>>>>>.>>....<..<<.<.<<<<.<<<..<<<<<< <<<<<<<...<.<<<<....<<<....>>>.>>>>.>..>>>>>>>>>>> >>..>>>.>>>>..>.>>...>.....<<<<<<<<<....>>>>>>>>>. ...

Receptor-Ligand Complex Structure Global view Local view Structure summary [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] PDB 6uo1 Pseudouridinylation of mRNA coding sequences alters translation. Resolution 2.95 Å Binding residue (original residue number in PDB) K49 I50 P52 R53 A60 K61 R64 K68 K71 R72 R74 I75 F81 Binding residue (residue number reindexed from 1) K30 I31 P33 R34 A41 K42 R45 K49 K52 R53 R55 I56 F62

Enzymatic activity Enzyme Commision number ?

Gene Ontology Molecular Function GO:0003735 structural constituent of ribosome GO:0019843 rRNA binding GO:0070181 small ribosomal subunit rRNA binding

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005840	ribosome
GO:1990904	ribonucleoprotein complex

View graph for Molecular Function

View graph for Biological Process

View graph for Cellular Component