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Structure of PDB 6i7o Chain AH Binding Site BS01

Receptor Information >6i7o Chain AH (length=120) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure] ALKVRTSATFRLPKTLKLARAPKYASKAVPHYNRLDSYKVIEQPITSETA MKKVEDGNILVFQVSMKANKYQIKKAVKELYEVDVLKVNTLVRPNGTKKA YVRLTADYDALDIANRIGYI

Ligand information >6i7o Chain BQ (length=3127) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure] uugaccucaaaucagguaggaguacccgcugaacuuaagcauaucaauaa gcggaggaaaagaaaccaaccgggauugccuuaguaacggcgagugaagc ggcaaaagcucaaauuugaaaucugguaccuucggugcccgaguuguaau uuggagagggcaacuuuggggccguuccuugucuauguuccuuggaacag gacgucauagagggugagaaucccguguggcgaggagugcgguucuuugu aaagugccuucgaagagucgaguuguuugggaaugcagcucuaagugggu gguaaauuccaucuaaagcuaaauauuggcgagagaccgauagcgaacaa guacagugauggaaagaugaaaagaacuuugaaaagagagugaaaaagua cgugaaauuguugaaagggaagggcauuugaucagacaggccagcaucag uuuugguggcaggauaaauccauaggaauguagcuugccucgguaaguau uauagccugugggaauacugccagcugggacugaggacugcgacguaagu caaggaugcuggcauaaugguuauaugccgcccgucuugaaacacggacc aaggagucuaacgucuaugcgaguguuuggguguaaaacccauacgcgua augaaagugaacguagguuggggccucgcaagaggugcacaaucgaccga uccugaugucuucggauggauuugaguaagagcauagcuguugggacccg aaagauggugaacuaugccugaauagggugaagccagaggaaacucuggu ggaggcucguagcgguucugacgugcaaaucgaucgucgaauuuggguau aggggcgaaagacuaaucgaaccaucuaguagcugguuccugccgaaguu ucccucaggauagcagaagcucguaucaguuuuaugagguaaagcgaaug auuagagguuccggggucgaaaugaccuugaccuauucucaaacuuuaaa uauguaagaaguccuuguuacuuaauugaacguggacauuugaaugaaga gcuuuuagugggccauuuuugguaagcagaacuggcgaugcgggaugaac cgaacguagaguuaaggugccggaauacacgcucaucagacaccacaaaa gguguuaguucaucuagacagccggacgguggccauggaagucggaaucc gcuaaggaguguguaacaacucaccggccgaaugaacuagcccugaaaau ggauggcgcucaagcguguuaccuauacucuaccgucaggguuaugaugc ccugacgaguaggcaggcguggaggucagugacgaagccuagaccguaag gucgggucgaacggccucuagugcagaucuuggugguaguagcaaauauu caaaugagaacuuugaagacugaaguggggaaagguuccacgucaacagc aguuggacguggguuagucgauccuaagagauggggaagcuccguuucaa aggccugcaggccaccaucgaaagggaauccgguuaagauuccggaaccu ggauauggauucuucacgguaacguaacugaauguggagacgucggcgcg agcccugggaggaguuaucuuuucuucuuaacagcuuaucaccccggaau ugguuuauccggagauggggucuuauggcuggaagaggccagcaccuuug cuggcuccggugcgcuugugacggcccgugaaaauccacaggaaggaaua guuuucaugccaggucguacugauaaccgcagcaggucuccaaggugaac agccucuaguugauagaauaauguagauaagggaagucggcaaaauagau ccguaacuucgggauaaggauuggcucuaagggucggacgaucaacuuag aacugguacggacaaggggaaucugacugucuaauuaaaacauagcauug cgauggucagaaagugauguugacgcaaugugauuucugcccagugcucu gaaugucaaagugaagaaauucaaccaagcgcggguaaacggcgggagua acuaugacucucuuaagguagccaaaugccucgucaucuaauuagugacg cgcaugaauggauuaacgagauucccacugucccuaucuacuaucuagcg aaaccacagccaagggaacgggcuuggcagaaucagcggggaaagaagac ccuguugagcuugacucuaguuugacauugugaagaguuucuuuacuuau ucaaugaagcggagcuggaauucauuuuccacguucuagcauucaagguc ccauucggggcugauccggguugaagacauugucagguggggaguuuggc uggggcggcacaucuguuaaacgauaacgcagauguccuaaggggggcuc auggagaacagaaaucuccaguagaacaaaaggguaaaagcccccuugau uuugauuuucagugugaauacaaaccaugaaaguguggccuaucgauccu uuagucccucggaauuugaggcuagaggugccagaaaaguuaccacaggg auaacuggcuuguggcagucaagcguucauagcgacauugcuuuuugauu cuucgaugucggcucuuccuaucauaccgaagcagaauucgguaagcguu ggauuguucacccacuaauagggaacgugagcuggguuuagaccgucgug agacagguuaguuuuacccuacugaugaauguuaccgcaauaguaauuga acuuaguacgagaggaacaguucauucggauaauugguuuuugcggcugu cugaucaggcauugccgcgaagcuaccauccgcuggauuauggcugaacg ccucuaagucagaauccaugcuagaacgcggugauuuugcuccacacaau auagauggauacgaauaaggcguccuuguggcgucgcugaaccauagcag gcuagcaacggugcacuuggcggaaaggccuugggugcuugcuggcgaau ugcaaugucauuuugcguggggauaaaucauuuguauacgacuuagaugu acaacgggguauuguaagcaguagaguagccuuguuguuacgaucugcug agauuaagccuuuguugucugauuugu ........................<<<<<<.....<<....>>......> >>>>.>.........<<....>>..<<<<<......<<.....>>..... >>>>>..[[[...........<<.<<<<<<...>>>>>>.>>........ .....<<<<<<<.<<<<<<<<<<<<<<<<<<<<.....<<<<......>> >>.(.......<<<......)>>>....>>>>>>>>..>>>>>>>>.... >>>>>>>>>>>........<<<<<<<........>>>>>>>.....(((( (..<<<<<<)))))..]]]............................... ...<<....>>...............<<<<....>>>>............ ......................<<<<<.<<<<<......<<<<<<<.<<< <<<<<<<<<<<<.....<<<<<<<<<......<<<<<......>>>>>.. .....>>>>>>>.>.>.>>>>>.>>>>>>>>>>........<<<....>> >.....>>>>>>>.....>>>>>.>>>>>..<<<<........>>>><<< <<<....<<<<<<.<<<<<<..<<<...<<<<.....>>>>...>>>... <<....>>.......<<<<<..<<<<<....>>>>>...>>>>>.<<<<< <<<...<<....>>...>>>.>>>.>>....>>>>>>.>>>>>>..<<.< ..<<<<<<<.....<<<<<<<<<..<<<....<<<<<<<....>>>>>>> .....>>>...<<<..<<.<<........>>>>.>>>....>>>>>>>>> ...<<.......>>......>>>>>>...>..>.>>..<<<<<<....<. <<<....>>>.><<<<<<<<<<...<<<.<<<<<<<.....<<<....<< <....<<<<...<<<<<<.....>>>>>>.>>>>....>>>..>.>>... ..>>>>>...<<<<.<<<<.<......>>>>>.>>>>.....>>>>>.>> >>>>>>.>>..<<<<.<<<<<.....>>>>>.>>>>....<<<......> >>...<<<<<<<..<<<<(((.....<<<<<<.....<<..........< <<.<<<<<<<<<<.......<<<<<.<<<...<<.........>>...>> >.........<<......>>...>>>>>...>>>>>>>>>>>>>...... ....))).>>...>>>>>>.>>>>..>>>>>>><<<<<<<<<......>> >>>>>>>....>>>>>><..<<<<<<<.<<......<<<<.<<<<....> >>>>>>>...>>>>>>>>>...>.....>>>>>><<.....<<.....<< <<<<.......>>>>>><<<<.....<<<<<.<<...<<<<<<...<<.. ...>>.>>>>>>....((<<<<<<...<<....<<<....>>>....... .<<<<<..>>>>>....>>....>>...<<<<<........>>>>>))<< <<.<<<<<<<.....<<<....>>>.......<<<<<<...<<<<.<<<< <<<<<<<<<<<<<<..{{{..>>>>>><...<<<<<....<<<<<<.... <<<.....>>>....>>>>>>.....>>>>>....><<<<<<<......> >>>>>>>>>>.>.>>>>>>>.>>>>.........>>>>>>.......... >>>..>>>>>>>>>>>>..>>.....<<......>>>>>>>.<<<<.... .>>>>..>>>>..<<<<.....<<<<<<<.<<.........<.....<<< <<...............>>>>><<.<<<<<<<<<<<..>>>>>..>>>>> >.>>............<<<<<<<<<..<<<.........>>>..<<<<<< <....<<<<.....>>>>......>>>>>>>...<<..<<<..<<<<<<. ...<<<.....<<<<....>>>>.....>>>.>>>>..>>>>><<<<<<. ......>>>>>>........<...........<<<<<.......>>>>>. ....>.....>>....>>.>>>>>>>..>..>>.>>>>>>>..>>>>>>. ...>>....<<<<<........>>>>>....[[[[[..{{{.{{...... [[[[.{{[[[[..<<<<<.<<<<<<<<..<<<<<<<...>>>>>>>...< <<<<.....<<<<..<<<..........>>>...............<<<< <<....>>>>>>..>>>>..>>>>>.....>>>>>>>>..>>>>>...<< <.....>>>..<<<<<<...........>>>>>>..<<...<<<<<<<.. .<<<<<<.......>>>>>>.....<<...(((>>....>>>>>>>...< <<.<<<<<.......>>>>.>>>>.<<<....>>>.>>))).......(( ((((..((((.>>>>>>))))))))))..........]]]]..}}]]]]. ......<<.<.<.<<<<<<...<<.......>>...>>>>>>...>>.>. >........<<<<.<<<<<<..<.<<<<<<<......>>>>>>>...>.< <<.........>>>.....>>>>>..>...>>>.>.....<<<<<<<... .>>>.>>>>....}}..}}}.]]]]]....<<<<<<<<..<<<<.<.<<< <<<...............>>>>>>.><<<<<...<<<<...<<<<<<<<< <<}}}.>>>>>..>>>>>>..>>>>..>>>>>.<<<<...<<<<<..... ......>>>>>...>>>>.>>>>....>>>>>>>>....<<<<<<.<<<. <<....<<..........<<<<<<.....>>>>>>......>>....... <<<<<<...<<<<<.<..<<<......>>>..>.>>>>>.>>>>>>.... .........>>.>>>.>>>>>>..<<<<<.<.............>..... <<<<<<<<<.<<<....<<<<....<<<<<......>>>>>...>>>>.. .>>>....>>>>.>>>>>..>>>>>..

Receptor-Ligand Complex Structure Global view Local view Structure summary [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] PDB 6i7o Collided ribosomes form a unique structural interface to induce Hel2-driven quality control pathways. Resolution 5.3 Å Binding residue (original residue number in PDB) A30 T31 R33 L34 P35 K39 L40 A41 R42 A43 K45 Y46 T71 K75 N91 K92 Y93 K109 N111 T112 V114 P116 K120 K121 Y123 R125 Binding residue (residue number reindexed from 1) A8 T9 R11 L12 P13 K17 L18 A19 R20 A21 K23 Y24 T49 K53 N69 K70 Y71 K87 N89 T90 V92 P94 K98 K99 Y101 R103

Enzymatic activity Enzyme Commision number ?

Gene Ontology Molecular Function GO:0003735 structural constituent of ribosome GO:0019843 rRNA binding

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005840	ribosome

View graph for Molecular Function

View graph for Biological Process

View graph for Cellular Component